@article{ATM11382,
author = {Ahmadou M. Jingi and Jean Jacques N. Noubiap and Mickael Essouma and Jean Joel R. Bigna and Jobert Richie N. Nansseu and Augustin Ellong and Côme Ebana Mvogo},
title = {Association of insulin treatment versus oral hypoglycaemic agents with diabetic retinopathy and its severity in type 2 diabetes patients in Cameroon, sub-Saharan Africa},
journal = {Annals of Translational Medicine},
volume = {4},
number = {20},
year = {2016},
keywords = {},
abstract = {Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease associated with multiple macro and microvascular complications, diabetic retinopathy (DR) being the commonest one. Recent literature has reported an increased risk of DR with insulin use.
Methods: We carried out a cross-sectional study at the Ophthalmology Department of the Douala General Hospital (DGH) during a 2-year period to explore the association between insulin treatment and both DR and its severity as compared with oral hypoglycemic agents (OHAs) in Cameroonian T2DM patients aged ≥35 years, and who were all screened for DR through eye examination including exhaustive retinal evaluation.
Results: In total, medical files of 134 T2DM patients were analyzed. The frequency of DR was 54.1% among patients on OHA and 73.9% among those on insulin treatment, giving an overall frequency of 57.5%. There were significantly more OHA treated patients than insulin treated patients (82.8% vs. 17.2%, P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/11382}
}