@article{ATM12488,
author = {Evangelia Athanasiou and Electra Michalopoulou-Manoloutsiou and Mattheos Bobos and Dimitris I. Hatzibougias and Paul Zarogoulidis and Nikolos Katsikogiannis and Eirini Sarika and Ilias Karapantzos and Nikolaos Barbetakis and Dimitrios Paliouras and Fotis Chatzinikolaou and Charalampos Charalampidis and Ioanna Kougioumtzi and Alexandros Kolettas and Andreas Bakas and Keraso Tzelepi and Efstratios Kalaitzis and Kosmas Tsakiridis},
title = {Coincidence of thymoma and breast cancer and in a 56-year-old female patient},
journal = {Annals of Translational Medicine},
volume = {4},
number = {22},
year = {2016},
keywords = {},
abstract = {We present a case of a 56-year-old female, with a familial history of breast, lung and brain cancer, which revealed a breast tumor, located in the upper outer quadrant of the left breast. During the routinely staging examinations, a 15 cm intrathoracic tumor was found in the upper left mediastinum, penetrating the pericardium and a smaller tumor, in the left side of parietal pleura. Core biopsies from both lesions, revealed a lobular carcinoma of the breast classic type, grade II (e-cadherin-, ER+, PR+, Her-2−, Ki-67 10%) and a B3 thymoma (CK19+, CD5+) penetrating the pericardium and the left lung. A synchronous removal of both tumors was scheduled, including median sternotomy and left intrapericardial pneumonectomy, followed by a modified radical left mastectomy and a sentinel lymph node biopsy. The postoperative course was uneventful. This case advocates that thymoma patients appear to have a predisposition towards developing additional neoplasms, as breast carcinoma. Clinicians should be aware of the increased incidence of extrathymic cancers, occurring in thymoma patients.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/12488}
}