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Myeloid-derived suppressor cell, arginase-1, IL-17 and cl-CD95L: an explosive cocktail in lupus?

   
@article{ATM12852,
	author = {Robin J. Flynn and Patrick Legembre},
	title = {Myeloid-derived suppressor cell, arginase-1, IL-17 and cl-CD95L: an explosive cocktail in lupus?},
	journal = {Annals of Translational Medicine},
	volume = {4},
	number = {24},
	year = {2016},
	keywords = {},
	abstract = {Myeloid-derived suppressor cells (MDSCs) (CD33+CD11b+) are a heterogenous population derived from immature myeloid cells consisting of two main subsets: CD15+CD66b+ granulocytic (G-MDSCs) and CD14+HLA-DR– monocytic (M-MDSCs) cells (1). G-MDSCs consist of relatively immature and pathologically activated neutrophils, whereas M-MDSCs are inflammatory monocytes (2). While MDSCs are associated with a poor clinical outcome in cancer, their role in chronic inflammatory diseases remains unclear probably because, among other explanations, the heterogeneity of this cellular population.},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/12852}
}