TY  - JOUR
AU  - Ashraf, Haseem
AU  - Krag-Andersen, Shella
AU  - Naqibullah, Matiullah
AU  - Minddal, Valentina
AU  - Nørgaard, Annette
AU  - Henriette Naur, Therese Maria
AU  - Myschetzky, Peter Sand
AU  - Clementsen, Paul Frost
PY  - 2017
TI  - Computer tomography guided lung biopsy using interactive breath-hold control: a randomized study
JF  - Annals of Translational Medicine; Vol 5, No 12 (June 30, 2017): Annals of Translational Medicine (Focus on “From Microbe to Microbiome: New Implication in Respiratory & Critical Care Medicine”)
Y2  - 2017
KW  - 
N2  -  Background:  Interactive breath-hold control (IBC) may improve the accuracy and decrease the complication rate of computed tomography (CT)-guided lung biopsy, but this presumption has not been proven in a randomized study.    Methods:  Patients admitted for CT-guided lung biopsy were randomized to biopsy either with (N=201) or without (N=206) IBC. Biopsy accuracy, procedure time, radiation, and complications were compared in the two groups. Predictors for pneumothorax were analyzed.    Results:  Procedures performed with the use of IBC (N=130) did not show higher biopsy accuracy (P=0.979) but were associated with a higher risk of pneumothorax (P=0.022) compared to procedures without the use of IBC (N=171). Overall, 50% of the biopsies were malignant, 13% were benign, and 33% were inconclusive (4% missing). Long needle time (P=0.037) and small nodule size (P=0.001) were predictors of pneumothorax.    Conclusions:  The use of IBC for CT-guided lung biopsy was not an advantage for unselected patients in our care, since it did not improve the biopsy accuracy and the risk of pneumothorax was increased.
UR  - https://atm.amegroups.org/article/view/15167