%0 Journal Article %T Over-the-scope clips versus standard endoscopic therapy as first-line treatment for bleeding peptic ulcer disease: a systematic review and meta-analysis %A Abosheaishaa, Hazem %A Youssef, Mohammed Y. %A Eldesouki, Mohamed H. %A Elgozair, Mohamad %A Iskander, Mina %A Elnaggar, Hossam %A Alzubaidy, Layth %A Abbas, Sharif %A Alzamzamy, Ahmed Elsayed %A Forlemu, Arnold %A Reddy, Madhavi %J Annals of Translational Medicine %D 2026 %B 2026 %9 %! Over-the-scope clips versus standard endoscopic therapy as first-line treatment for bleeding peptic ulcer disease: a systematic review and meta-analysis %K %X Peptic ulcer bleeding remains a significant cause of non-variceal upper gastrointestinal bleeding (NVUGIB). While over-the-scope clips (OTSC) are increasingly used as rescue therapy, their efficacy as first-line treatment remains unclear. The aim of this study is to evaluate the efficacy and safety of OTSC compared to standard endoscopic therapy (SET) as a first-line treatment in patients with bleeding peptic ulcer disease (PUD). %U https://atm.amegroups.org/article/view/153083 %V 14 %N 2 %P 14 %@ 2305-5847