@article{ATM17259,
author = {Manyoo A. Agarwal and Lohit Garg and Carl J. Lavie and Guy L. Reed and Rami N. Khouzam},
title = {Impact of family history of coronary artery disease on in-hospital clinical outcomes in ST-segment myocardial infarction},
journal = {Annals of Translational Medicine},
volume = {6},
number = {1},
year = {2017},
keywords = {},
abstract = {Background: Patients with a family history of coronary artery disease (FHxCAD) are at increased risk for development of myocardial infarction (MI). However, the data on the influence of FHxCAD on in-hospital clinical outcomes post ST-segment myocardial infarction (STEMI) is limited. Hence, we evaluated the impact of FHxCAD on in-hospital clinical outcomes post STEMI in an unselected nationwide cohort.
Methods: Nationwide Inpatient Sample (NIS) database [2003–2011] was used to compare differences in all-cause in-hospital mortality and adverse clinical events (cardiogenic shock, acute cerebrovascular events and use of intra-aortic balloon pump) between patients with and without FHxCAD.
Results: A total of 2,123,492 STEMI admissions were identified, of which 7.4% (n=158,079) patients were with FHxCAD and 92.6% (n=1,965,413) were without FHxCAD. The FHxCAD group had lower inhospital mortality [1.4% vs. 8.1%; adjusted odds ratio (OR): 0.42, 95% confidence interval (CI): 0.41–0.44; P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/17259}
}