@article{ATM17686,
author = {Jessica L. Churchill and Nipun Sodhi and Anton Khlopas and Nicolas S. Piuzzi and Sarah E. Dalton and Morad Chughtai and Assem A. Sultan and Steven Jones and Nick Williams and Peter M. Bonutti and Michael A. Mont},
title = {Total knee arthroplasty fibrosis following arthroscopic intervention},
journal = {Annals of Translational Medicine},
volume = {5},
number = {Suppl 3},
year = {2017},
keywords = {},
abstract = {Background: Although arthroscopy is generally considered to be a relatively benign procedure with limited trauma to periarticular soft tissues, post-arthroscopic bleeding as well as osmolality differences between the normal saline used to irrigate and the native synovial fluid (282 vs. 420 mOs) can lead to capsular reactions. Therefore, the purpose of this study was to evaluate whether capsular reaction occurred after knee arthroscopy, by comparing a matched cohort of patients who either did or did not undergo prior arthroscopic surgery. Specifically, we compared histological features such as: (I) synovial thickness; (II) cellularity; and (III) the amount of fibrous tissue for each cohort.
Methods: Prior to their total knee arthroplasty (TKA), 40 consecutive patients who had previously undergone arthroscopy were matched to 40 consecutive patients who had not. During each patient’s TKA, a biopsy of the capsule and fat pad was taken and formalin sections were sent to pathology to assess for synovial thickness, cellularity, and the amount of fibrous tissue. The pathologist was blinded to the groupings. Findings for all histologic features were classified as equivocal, slight to moderate, and moderate to severe.
Results: There were a significantly higher proportion of patients who had increased synovial thickness in the prior arthroscopy group as compared to the no-prior arthroscopy group (97.5% vs. 0%, P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/17686}
}