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Noninvasive cancer biomarkers in solid malignancies: circulating tumor DNA—clinical utility, current limitations and future perspectives

  
@article{ATM19686,
	author = {Debora de Melo Gagliato and Denis L. Fontes Jardim},
	title = {Noninvasive cancer biomarkers in solid malignancies: circulating tumor DNA—clinical utility, current limitations and future perspectives},
	journal = {Annals of Translational Medicine},
	volume = {6},
	number = {11},
	year = {2018},
	keywords = {},
	abstract = {Since the first publication of human genome, the cancer community witnessed a substantial progress in available technologies to genetically characterize tumor  samples (1). Turnaround times and costs are rapidly decreasing, along with the availability of a myriad of tests using a variety of samples other than conventional biopsy tumor tissue. Detection of circulating tumor DNA (ctDNA) in cancer patients has the potential to offer a precise and non-invasive tumor evaluation. Ranging from cancer diagnosis to prognostic stratification, and treatment guidance, applicability of ctDNA may allow its broad incorporation into clinical practice (2-4).},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/19686}
}