@article{ATM19890,
author = {Wilbert S. Aronow and Tatyana A. Shamliyan},
title = {Blood pressure targets for hypertension in patients with type 2 diabetes},
journal = {Annals of Translational Medicine},
volume = {6},
number = {11},
year = {2018},
keywords = {},
abstract = {Background: Clinical guidelines vary in determining optimal blood pressure targets in adults with diabetes mellitus.
Methods: We systematically searched PubMed, EMBASE, Cochrane Library, and clinicaltrials.gov in March 2018; conducted random effects frequentist meta-analyses of direct aggregate data; and appraised the quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology.
Results: From eligible 14 meta-analyses and 95 publications of randomized controlled trials (RCT), only 6 RCTs directly compared lower versus higher blood pressure targets; remaining RCTs aimed at comparative effectiveness of hypotensive drugs. In adults with diabetes mellitus and elevated systolic blood pressure (SBP), direct evidence (2 RCTs) suggests that intensive target SBP },
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/19890}
}