@article{ATM20488,
author = {Ruxing Wu and Fei Liu and Ping Peng and Hong Qiu and Huihua Xiong and Shiying Yu and Xiaoyuan Huang and Hanwang Zhang and Liang Zhuang},
title = {Tumor stress-induced phosphoprotein 1 as a prognostic biomarker for breast cancer},
journal = {Annals of Translational Medicine},
volume = {6},
number = {15},
year = {2018},
keywords = {},
abstract = {Background: Recent studies suggested an important relationship between tumor stress-induced phosphoprotein 1 (STIP1) and cancer. However, the expression of STIP1 in breast cancer tissues and its relationship with clinical characteristics and survival have not been investigated in humans. The aim of our work was to evaluate the association of STIP1 and the prognosis of breast cancer patients.
Methods: The included patients were followed-up by telephone and through a review of their outpatient records. The expression of STIP1 was assessed by immunohistochemistry (IHC). The 5-year recurrence-free survival (RFS) rate and the 5-year overall survival (OS) rate were the prognostic indicators evaluated by the Kaplan-Meier method. Univariate and multivariate analyses employing a Cox regression model were used to calculate hazard ratios (HRs).
Results: The rate of high expression of STIP1 was 55.3% (126/228) in breast cancer tissues and 14.9% (34/228) in adjacent normal tissues (χ2=81.495, P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/20488}
}