@article{ATM20902,
author = {Rupak Desai and Kiranmayi Kakumani and Hee Kong Fong and Bhrugesh Shah and Daniyal Zahid and Dipen Zalavadia and Rajkumar Doshi and Hemant Goyal},
title = {The burden of cardiac arrhythmias in sarcoidosis: a population-based inpatient analysis},
journal = {Annals of Translational Medicine},
volume = {6},
number = {17},
year = {2018},
keywords = {},
abstract = {Background: Cardiac involvement in the sarcoidosis is known to ensue with diverse clinical forms and its investigation is challenging at times. This article features the under-perceived burden, patterns, and outcomes of different arrhythmias, which may have a prognostic significance in patients with sarcoidosis.
Methods: We queried the National Inpatient Sample (NIS) for 2010–2014 to recognize sarcoidosis, arrhythmia, and comorbidities affecting hospitalizations. The nationwide estimates were attained using discharge records. We assessed incidence and trends in sarcoidosis-related arrhythmia and consequential inpatient mortality, hospital length of stay (LOS), hospitalization charges and predictors of mortality with multivariate analysis.
Results: We identified 369,285 sarcoidosis-related hospitalizations. Of these, nearly one-fifth suffered from arrhythmias (n=73,424). The sarcoidosis patients developing arrhythmias were older (61.9 vs. 56.0 years) compared to those without. Males had the higher incidence of arrhythmias compared to females. Atrial fibrillation (Afib) (10.97%) was the most common subtype, followed by ventricular tachycardia (1.97%). There was a rising trend in arrhythmia-related hospital admissions and mortality among sarcoidosis, with Afib incidence displaying the highest increase. Traditional cardiac comorbidities were higher in the sarcoid-arrhythmia group. The arrhythmia group had significantly higher mortality (3.7% vs. 1.5%), mean hospital LOS (6.4 vs. 5.2 days) and hospital charges (\$64,118 vs. \$41,565) compared to non-arrhythmia group (P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/20902}
}