%0 Journal Article %T The fecal microbiome directly drives immune activation in HIV infection %A Tincati, Camilla %A Ancona, Giuseppe %A Marchetti, Giulia %J Annals of Translational Medicine %D 2018 %B 2018 %9 %! The fecal microbiome directly drives immune activation in HIV infection %K %X Immune activation is a hallmark of human immunodeficiency virus (HIV) infection: it causes progression to the acquired immunodeficiency syndrome (AIDS), impaired CD4+ T-cell reconstitution on suppressive combination antiretroviral therapy (cART) and contributes to non-infectious comorbidities (1-6). Understanding the mechanisms whereby immune activation arises is thus crucial for the elaboration of novel therapeutic interventions in the setting of HIV infection. %U https://atm.amegroups.org/article/view/21775 %P S45 %@ 2305-5847