@article{ATM22496,
author = {Dimitrios N. Katsaras and Chrysa K. Arvaniti and Panayota G. Flevari and Georgios V. Giannopoulos and Chrysanthi Z. Batistaki and Vassilios E. Stassinos and Georgia G. Kostopanagiotou and Spyridon G. Deftereos and Efstathios K. Iliodromitis and Dionyssios I. Leftheriotis},
title = {Sphenopalatine ganglion block: an external gate to modulate cardiac autonomic tone and suppress premature ventricular beats?},
journal = {Annals of Translational Medicine},
volume = {6},
number = {23},
year = {2018},
keywords = {},
abstract = {Background: Autonomic modulation is used for treating various cardiovascular diseases, such as cardiac arrhythmias. Sphenopalatine ganglion (SPG) block is an easy, non-invasive therapy for migraine with a potential cardiovascular impact that remains unclear. In this study, we sought to assess the effect of SPG block on cardiac autonomic tone, as expressed by heart rate variability (HRV), and on ventricular arrhythmogenesis.
Methods: Forty patients (14 male and 26 female) suffering from migraine were randomized by 1:1 to SPG block or placebo (controls) and HRV parameters were evaluated 1 hour before and hourly after the intervention. Twenty-four additional patients (11 men and 13 women) with premature ventricular contractions (PVCs) from the right ventricular outflow tract underwent the same randomization and the number of PVCs was assessed during 1 hour before and every hour after treatment. Values were summarized as median (1st–3rd quartile).
Results: During the first four hours after SPG block, an increase in mean RR [883 (IQR, 869–948) vs. 839 (IQR, 806–887) ms at baseline, P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/22496}
}