@article{ATM22988,
author = {Nuriel Moghavem and Heather A. Wakelee and Seema Nagpal},
title = {Case closed: another prophylactic cranial irradiation trial for stage 3 non-small cell lung cancer fails to improve overall survival},
journal = {Annals of Translational Medicine},
volume = {6},
number = {Suppl 2},
year = {2018},
keywords = {},
abstract = {In a recent study published by De Ruysscher et al. (1), the use of prophylactic cranial irradiation (PCI) significantly reduced the rate of symptomatic brain metastasis development in patients with stage 3 non-small-cell lung cancer (NSCLC) at 2 years. Patients with WHO performance status 0–2 undergoing chemoradiotherapy with or without surgery for their stage 3 disease were randomized to an observation arm or a treatment arm that underwent PCI (36 Gy in 18 fractions, 30 Gy in 12 fractions, or 30 Gy in 10 fractions).},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/22988}
}