@article{ATM23335,
author = {Tara Moore and Nipun Sodhi and Angad Kalsi and Rushabh M. Vakharia and Joseph O. Ehiorobo and Hiba K. Anis and Kristina Dushaj and Vivian Papas and Giles Scuderi and Scott Nelson and Martin W. Roche and Michael A. Mont},
title = {A nationwide comparative analysis of medical complications in fibromyalgia patients following total knee arthroplasty},
journal = {Annals of Translational Medicine},
volume = {7},
number = {4},
year = {2019},
keywords = {},
abstract = {Background: Fibromyalgia is a disease primarily characterized by chronic widespread pain and associated symptoms of fatigue, mild cognitive impairment, and sleep disturbance. The condition affects 1% to 6% of the general population in the United States and is more commonly diagnosed in women (2:1 ratio). There is evidence to suggest that fibromyalgia patients may be more at risk of postoperative complications. The rate of total knee arthroplasties (TKAs) performed worldwide is escalating and thus it is expected that the proportion of fibromyalgia patients under orthopaedic care will increase accordingly. However, the literature on TKA outcomes in this subpopulation is limited. We assessed whether fibromyalgia patients have a higher likelihood of developing medical complications compared to a matched cohort of non-fibromyalgia patients following TKA. Specifically, we assessed the likelihood of developing (I) any medical complication and (II) specific medical complications.
Methods: Using the Medicare Standard Analytical Files of the PearlDiver supercomputer, patients who underwent a TKA between 2005 and 2014 were queried. Propensity score matching was used to match patients with and without fibromyalgia in a 1:1 ratio based on age, sex, and the Charlson Comorbidity Index (CCI). A total cohort of 305,510 patients (female =242,198; male =59,810; and unknown =3,502) with (n=152,755) and without fibromyalgia (n=152,755) was identified. Statistical analyses involved the calculation of odds ratios, 95% confidence intervals (95% CI), and P values (},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/23335}
}