@article{ATM24145,
author = {Man-Man Han and Jin-Fang Sun and Xiang-Hui Su and You-Fan Peng and Hemant Goyal and Chun-Hua Wu and Xiang-Yun Zhu and Ling Li},
title = {Probiotics improve glucose and lipid metabolism in pregnant women: a meta-analysis},
journal = {Annals of Translational Medicine},
volume = {7},
number = {5},
year = {2019},
keywords = {},
abstract = {Background: This study aims to assess the effects of probiotic supplementation on the maternal metabolism and the risk of development of gestational diabetes mellitus (GDM) in the pregnant women by a meta-analysis of relevant randomized controlled trials (RCTs).
Methods: The medical literature was searched from PubMed, Web of Science and the Cochrane Library since inception to October 2017. Two investigators independently performed the data extraction and quality assessment. The mean differences (MD) or standardized mean differences (SMD) or relative risk (RR) with 95% confidence intervals (CIs) were calculated with the random-effects model.
Results: From 648 citations, a total of ten RCTs published in 13 articles with 1,139 participants met the inclusion criteria. The meta-analysis showed that probiotics supplementation effectively reduced the fasting blood glucose (FBG) levels (MD −0.11 mmol/L, P=0.0003), serum insulin levels (MD −2.06 μU/mL, P},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/24145}
}