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Long-term impact of prognostic nutritional index in cervical esophageal squamous cell carcinoma patients undergoing definitive radiotherapy

  
@article{ATM25353,
	author = {Yaqing Dai and Xiaobin Fu and Tingting Li and Qiwei Yao and Liyu Su and Huiyan Su and Jiancheng Li},
	title = {Long-term impact of prognostic nutritional index in cervical  esophageal squamous cell carcinoma patients undergoing  definitive radiotherapy},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {8},
	year = {2019},
	keywords = {},
	abstract = {Background: The prognostic nutritional index (PNI) has been found to have prognostic value in several cancers, and we aimed to determine its predictive value for the long-term prognosis of cervical esophageal squamous cell carcinoma (CESCC) patients treated with chemoradiotherapy (CRT).
Methods: The data for 106 CESCC patients who received radiotherapy with or without chemotherapy at the Cancer Hospital of Fujian Medical University from June 1, 2000 to December 31, 2015 were retrospectively analyzed. According to serum measurements taken before therapy, the PNI was calculated as albumin (g/L) + 5 × total lymphocyte count. The association between PNI and overall survival (OS) was determined by the Kaplan-Meier method and Cox proportional regression model analysis.
Results: The median follow-up time was 19 months. The optimal cutoff value for PNI was calculated to be 48.15, and patients were divided into a low PNI group (},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/25353}
}