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BRAF mutant metastatic colorectal cancers: new arrows in our quiver

   
@article{ATM28956,
	author = {Chiara Cremolini and Roberto Moretto and Gemma Zucchelli and Alfredo Falcone},
	title = {BRAF mutant metastatic colorectal cancers: new arrows in our quiver},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {Suppl 8},
	year = {2019},
	keywords = {},
	abstract = {BRAF mutations occur in 8–12% of metastatic colorectal cancers (mCRC) and more than 95% of them consist in a T>A transversion in exon 15 resulting in an amino acid substitution from valine to glutamic acid (V600E) that is able to increase BRAF kinase activity by approximately  10-fold (1,2).},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/28956}
}