@article{ATM30777,
author = {Arpit Rao and Emmanuel S. Antonarakis},
title = {Circulating tumor cell-based or tissue biopsy-based AR-V7 detection: which provides the greatest clinical utility?},
journal = {Annals of Translational Medicine},
volume = {7},
number = {Suppl 8},
year = {2019},
keywords = {},
abstract = {Metastatic castration-resistant prostate cancer (mCRPC) is a condition characterized by cancer progression in the setting of low serum testosterone levels (1,2), and represents the lethal phase of the disease. Biologically, the development of castration-resistance occurs through a multitude of primarily androgen receptor (AR)-dependent mechanisms such as AR amplification, AR mutation, AR splice variant expression, and increase in synthesis of intratumoral and adrenal androgens through CYP17 and other pathways (3,4).},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/30777}
}