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Symptomatic late-onset hypogonadism but normal total testosterone: the importance of testosterone annual decrease velocity

   
@article{ATM32170,
	author = {Sandro La Vignera and Rosita A. Condorelli and Aldo E. Calogero and Rossella Cannarella and Laura M. Mongioì and Ylenia Duca and Laura Cimino and Filippo Giacone and Antonio Aversa},
	title = {Symptomatic late-onset hypogonadism but normal total testosterone: the importance of testosterone annual decrease velocity},
	journal = {Annals of Translational Medicine},
	volume = {8},
	number = {5},
	year = {2019},
	keywords = {},
	abstract = {Several lines of evidence suggest that a decline of serum testosterone levels occur in the aging male. This condition is called late-onset hypogonadism (LOH). Current guidelines suggest testosterone replacement therapy (TRT) when total testosterone (TT) is lower than 9.2 nmol/L. However, the clinical management of patients showing signs and symptoms suggestive for LOH but with TT in the lowest quartile of the normal range and/or having higher than the expected testosterone annual reduction velocity is not covered. This editorial aims to discuss this hot topic, suggesting a possible management.},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/32170}
}