@article{ATM32830,
author = {Emily S. Clausen and Lorenzo Zaffiri},
title = {Infection prophylaxis and management of viral infection},
journal = {Annals of Translational Medicine},
volume = {8},
number = {6},
year = {2019},
keywords = {},
abstract = {Viral infections are associated with significant morbidity and mortality in lung transplant recipients. Importantly, several viral infections have been associated with the development of chronic lung allograft dysfunction (CLAD). Community-acquired respiratory viruses (CARV) such as influenza and respiratory syncytial virus (RSV), are frequently associated with acute and chronic rejection. Cytomegalovirus (CMV) remains a significant burden in regards to morbidity and mortality in lung transplant recipients. Epstein-Barr virus (EBV) is mostly involved with the development of post-transplant lymphoproliferative disorder (PTLD), a lymphoid proliferation that occurs in the setting of immunosuppression. On the other hand, the development of direct acting antivirals for hepatitis C virus (HCV) is changing the use of HCV- positive organs in transplantation. In this article we will focus on reviewing common viral infections that have a significant impact on lung transplant recipients looking at epidemiology, prevention and potential treatment.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/32830}
}