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Maternal serum pentraxin 3 level in early pregnancy for prediction of gestational diabetes mellitus

   
@article{ATM32886,
	author = {Xiaoxian Qu and Jingyi Zhuang and Chuanlu Xu and Zisheng Ai and Ling Yuan and Yuping Tang and Qun Shu and Yirong Bao and Huan Han and Hao Ying},
	title = {Maternal serum pentraxin 3 level in early pregnancy for prediction of gestational diabetes mellitus},
	journal = {Annals of Translational Medicine},
	volume = {7},
	number = {23},
	year = {2019},
	keywords = {},
	abstract = {Background: Our study aimed to reveal the relationship of maternal pentraxin 3 (PTX3)’s serum concentrations in early pregnancy with gestational diabetes mellitus (GDM) and to explore its potential in the prediction of GDM.
Methods: Totally 824 pregnant women were enrolled and divided into a GDM group and a normal glucose tolerance (NGT) group, whose maternal fasting serum PTX3 levels, plasma glucose and insulin were collected. The beta cell function index and quantitative insulin sensitivity check index (QUICKI) was calculated and a homeostatic model assessment of insulin resistance (HOMA-IR) was used with SPSS 22 software used for statistical analysis.
Results: Of all subjects, 13.59% developed GDM. Compared to the NGT group, the PTX3 level was increased in the GDM group (1.48 vs. 1.52 ng/mL, P},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/32886}
}