@article{ATM33582,
author = {Ming Xue and Shi Zhang and Jianfeng Xie and Xiwen Zhang and Feng Liu and Yingzi Huang and Ling Liu and Songqiao Liu and Fengmei Guo and Yi Yang and Weiping Yu and Haibo Qiu},
title = {Differential expression of genes associated with T lymphocytes function in septic patients with hypoxemia challenge},
journal = {Annals of Translational Medicine},
volume = {7},
number = {24},
year = {2019},
keywords = {},
abstract = {Background: This study aimed to assess gene expression alterations related to T lymphocytes function and explore their potential association with hypoxemia among septic patients.
Methods: This is a retrospective cohort clinical study with laboratory investigations. We studied patients enrolled in sepsis biological specimen bank from Department of Critical Care Medicine, Zhongda Hospital, fulfilling consensus criteria for sepsis without any documented immune comorbidity admitted in ICU within 48 h after onset with whole blood samples drawn within 24 h of admission. Whole genome expression by microarray assay (Human LncRNA Microarray V4.0) was compared in hypoxemia cohort versus without. Differentially expressed (DE) genes with >1 log2[fold change (FC)] and false discovery rate (FDR) },
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/33582}
}