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Top-down proteomics—a near-future technique for clinical diagnosis?

   
@article{ATM34388,
	author = {Lidong He and Alan L. Rockwood and Archana M. Agarwal and Lissa C. Anderson and Chad R. Weisbrod and Christopher L. Hendrickson and Alan G. Marshall},
	title = {Top-down proteomics—a near-future technique for clinical diagnosis?},
	journal = {Annals of Translational Medicine},
	volume = {8},
	number = {4},
	year = {2020},
	keywords = {},
	abstract = {We thank Dr. Laszlo Prokai, Dr. Jae-Seok Kim, and Dr. Hyun Sik Kim for their insightful editorial commentaries on our recent publication “Diagnosis of hemoglobinopathy and β-thalassemia by 21 Tesla Fourier transform ion cyclotron resonance mass spectrometry and tandem mass spectrometry of hemoglobin from blood” (1-3). As described by the editorial authors, 21 Tesla Fourier transform ion cyclotron resonance mass spectrometry (21 T FT-ICR MS) and top-down MS/MS set a new benchmark for precision diagnosis of hemoglobinopathies and thalassemia with fast sample preparation (dilute and infuse) and data acquisition (3 min).},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/34388}
}