@article{ATM4336,
author = {Wei-Hai Xu and Ming-Li Li and Jing-Wen Niu and Feng Feng and Zheng-Yu Jin and Shan Gao},
title = {Luminal thrombosis in middle cerebral artery occlusions: a high-resolution MRI study},
journal = {Annals of Translational Medicine},
volume = {2},
number = {8},
year = {2014},
keywords = {},
abstract = {Background and purpose: High signals within occluded vessels on T1-weighted fat-suppressed images (HST1) are highly suggestive of luminal thrombosis. We sought to investigate the feasibility of in vivo identification of luminal thrombosis in middle cerebral artery (MCA) occlusions using high-resolution magnetic resonance imaging (HR-MRI).
Methods: We retrospectively reviewed the HR-MRI data of 25 patients with unilateral symptomatic MCA occlusion. HST1 were defined as an area of high signal within the cross-section of occluded MCA, the intensity of which was >150% of the signal of adjacent muscles. The prevalence of HST1 and their relationship to infarct sizes and infarct patterns were analyzed.
Results: The average time from stroke onset to HR-MRI examination was 9±6 days. There were 18 (72%) occluded vessels with HST1 on HR-MRI. HST1 were observed in 5/7 patients with a large territory infarct (≥1/3 MCA distribution) and 13/18 patients without (P=0.37). In the patients with non-large territory infarcts, the presence of HST1 was similar in those with and without border zone infarcts (9/13 vs. 4/5, P=0.42).
Conclusions: It’s feasible to in vivo identify luminal thrombosis in occluded MCA. HR-MRI is a potentially powerful tool for investigating the mechanisms of stroke due to MCA occlusions.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/4336}
}