@article{ATM5482,
author = {Cong Dai and Min Jiang and Ming-Jun Sun},
title = {Innate immunity and adaptive immunity in Crohn’s disease},
journal = {Annals of Translational Medicine},
volume = {3},
number = {3},
year = {2015},
keywords = {},
abstract = {Crohn’s Disease (CD) is systemic immune disorder affecting the gastrointestinal tract with frequent extraintestinal manifestations. Generally, CD is considered as a polygenic immune disorder with complex multifactor etiology. Specifically, CD mainly occurs in susceptible individuals in whom upon environmental and commensal microbiota triggers a sustained disturbed mucosal immune reaction. And the chronic unrestrained inflammatory response in CD is mainly driven by a disintegrated host immune regulatory network.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/5482}
}