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Current progress in genetic research of adolescent idiopathic scoliosis

   
@article{ATM6044,
	author = {Zezhang Zhu and Leilei Xu and Yong Qiu},
	title = {Current progress in genetic research of adolescent idiopathic scoliosis},
	journal = {Annals of Translational Medicine},
	volume = {3},
	number = {Suppl 1},
	year = {2015},
	keywords = {},
	abstract = {Previous genetic linkage analysis and candidate gene association analysis have unveiled dozens of variants associated with the development of adolescent idiopathic scoliosis (AIS), which however can seldom be replicated in different ethnics. Recently, two genome-wide association studies of AIS performed in Japan revealed that  LBX1  gene and  GPR126  gene could play a role in the etiopathogenesis of the disease. Since the association between these two genes and AIS were successfully validated in the Caucasian and the Chinese population,  LBX1  gene and  GPR126  gene were the most reliable genetic variants underling the development of AIS.},
	issn = {2305-5847},	url = {https://atm.amegroups.org/article/view/6044}
}