@article{ATM6230,
author = {Yo Mabuchi and Hideyuki Okano},
title = {Human somatic stem cell-based therapy for cartilage regeneration},
journal = {Annals of Translational Medicine},
volume = {3},
number = {Suppl 1},
year = {2015},
keywords = {},
abstract = {Clinical investigations using human somatic tissue derived stem cells for a variety of different diseases have been performed. Neural crest-derived stem cells exhibit somatic organization, can contribute to mesenchymal stem/stromal cells (MSCs) (1) and are used for cartilage treatment, bone reconstruction and anti-inflammatory treatments for diseases. The most common cell source for cartilage treatment is MSCs (2,3). Many clinical studies have used neural crest-derived stem cells (or MSCs) from different tissues and different methodologies. These differences in the generation of somatic tissue-derived stem cells have led to variable results in clinical studies. Although stem cell properties have been poorly characterized, human trials are presently under way.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/6230}
}