@article{ATM7250,
author = {Antonio Neto and Azore-Dee Bradshaw and Zhiheng Pei},
title = {Microbiome, a new dimension in cancer research},
journal = {Annals of Translational Medicine},
volume = {3},
number = {16},
year = {2015},
keywords = {},
abstract = {Recent reports on microbiome leading to or in association with cancer have surfaced in the medical science field. The results may impact clinical management as new concepts may provide a glimpse of a new world for cancer diagnosis, therapy and prevention. There will be profound implications for the discipline of medicine and oncology and for how laboratory diagnosticians relate to medicine as a whole. This editorial will provide a succinct, but challenging, analysis from a major article on the subject of cancer and microbiome, and how we anticipate the field of medical oncology will change during the next 5 to 10 years. In the Science publication of April 2015, Garrett highlights several mechanisms through which microbes and microbiota contribute to the development of cancer, whether by enhancing or diminishing a host’s risk. The mechanisms fall into three categories: (I) modifying the balance of host cell proliferation and death; (II) piloting the function of the immune system; and (III) affecting the breakdown of host-generated factors, ingested food staples, and pharmaceuticals.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/7250}
}