@article{ATM8610,
author = {Ting-Ting Qin and Hai-Quan Kang and Ping Ma and Peng-Peng Li and Lin-Yan Huang and Bing Gu},
title = {SOS response and its regulation on the fluoroquinolone resistance},
journal = {Annals of Translational Medicine},
volume = {3},
number = {22},
year = {2015},
keywords = {},
abstract = {Bacteria can survive fluoroquinolone antibiotics (FQs) treatment by becoming resistant through a genetic change—mutation or gene acquisition. The SOS response is widespread among bacteria and exhibits considerable variation in its composition and regulation, which is repressed by LexA protein and derepressed by RecA protein. Here, we take a comprehensive review of the SOS gene network and its regulation on the fluoroquinolone resistance. As a unique survival mechanism, SOS may be an important factor influencing the outcome of antibiotic therapy in vivo.},
issn = {2305-5847}, url = {https://atm.amegroups.org/article/view/8610}
}