Abstract
AB012. Assessment of quality of life, fatigue and sleep quality in patients with obstructive sleep apnea syndrome
Paschalina Tiga1, Maria Antoniadou1,2, Areti Batzikosta1, Evangelia Nena3, Athanasios Voulgaris4, Maria Xanthoudaki4, Rodopi Sotiropoulou4, Anestis Ganitis4, Despoina Kotakidou4, Marios Froudarakis4, Paschalis Steiropoulos1,4
1Master Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;2General Hospital of Imathia, Veroia, Greece;3Laboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, Alexandroupolis, Greece;4Department of Pulmonology, University General Hospital of Evros, Alexandroupolis, Greece
Background: Aim of the study was to assess the association between quality of life (QoL), reported fatigue and quality of sleep with the severity of obstructive sleep apnea syndrome (OSAS).
Methods: Consecutive individuals (n=376) examined with full polysomnography for suspected OSAS completed the following questionnaires: WHO-5 Well-Being Index, Fatigue Severity Scale (FSS), and Pittsburg Sleep Quality Index (PSQI) for the assessment of QoL, fatigue and sleep quality respectively.
Results: Mean age of the study population was 55.22 years and 74.7% of them were males. Subjects were divided in 4 groups according to their Apnea-Hypopnea Index (AHI): control group n=66 (17.3%), mild OSAS n=77 (20.5%), moderate OSAS n=71 (18.9%) and severe OSAS n=162 (43.2%). The majority of participants (65.7%) had a PSQI score >5 indicative of poor sleep quality while WHO-5 and FSS scores were abnormal (i.e. score <13 and score >36, respectively) in 46.5% and 45.8% of subjects respectively. No significant differences in QoL (WHO-5), sleep quality (PSQI) and in reported fatigue (FSS) between the 4 groups were observed. Logistic regression analysis revealed a significant inverse correlation between mean SpO2 during sleep with total PSQI score (OR 0.870, 95% CI: 0.759–0.997, P=0.045) and FSS score (OR 0.852, 95% CI: 0.762–0.952, P=0.005).
Conclusions: The majority of OSAS patients have impaired sleep quality, while almost half of them have poor quality of life and fatigue. Nocturnal hypoxemia is associated with poor sleep quality and daytime fatigue in this line of patients.
Keywords: Obstructive sleep apnea syndrome (OSAS); quality of life (QoL); sleep quality
doi: 10.21037/atm.2016.AB012
Cite this abstract as: Tiga P, Antoniadou M, Batzikosta A, Nena E, Voulgaris A, Xanthoudaki M, Sotiropoulou R, Ganitis A, Kotakidou D, Froudarakis M, Steiropoulos P. Assessment of quality of life, fatigue and sleep quality in patients with obstructive sleep apnea syndrome. Ann Transl Med 2016;4(22):AB012. doi: 10.21037/atm.2016.AB012
