CK1δ: an exploitable vulnerability in breast cancer

We do appreciate the interest and perspectives of Drs. Cheong and Virshup, who succinctly summarize and highlight the advances of our original manuscript (1). In addition to stressing the potential translational importance of our studies, Drs. Cheong and Virshup also note that our studies inevitably raise important questions. Here we elaborate on the questions raised in their perspective.