Erratum to Transthyretin-induced increase in circ_0007411 represses neovascularization of human retinal microvascular endothelial cells in hyperglycemia via the miR-548m/PTPN12/SKP1/EGFR pathway

Erratum to: Ann Transl Med 2022;10:556.

This article (1) titled “Transthyretin-induced increase in circ_0007411 represses neovascularization of human retinal microvascular endothelial cells in hyperglycemia via the miR-548m/PTPN12/SKP1/EGFR pathway” (doi: 10.21037/atm-22-1276), unfortunately contains an error in the image of Figure 4A, the Evans Blue staining for mouse retina. An incompletely integrated retina of STZ + shPTPN12 group was used at the site for STZ group accidentally.

Figure 4A of the original article:

The correct version of Figure 4A, containing the correct data for the STZ group in Figure 4A, is shown below.

Figure 4 The effects of PTPN12 in STZ-induced DR mice. (A,B) Stained with Evans blue, the retinal vascular leakage was detected (scale bar =100 µm). After trypsin digestion of the retina (C) (stained with periodic acid-Schiff, scale bar =25 µm), the number of acellular capillaries (D) and the hRECs:pericytes ratio (E) were counted (red arrows, the acellular capillaries; green arrows, the maintained pericytes; blue arrows, the lost pericytes). (F) In prepared 5-µm sections of dehydrated retina and sclera, the detachment between retina and choroid was marked with a red rectangle (H&E staining, scale bar =25 µm). Error bars represent the mean ± SD of at least triplicate experiments. *, P<0.05; **, P<0.01. DR, diabetic retinopathy; hRECs, human retinal microvascular endothelial cells; H&E, hematoxylin and eosin; NC, negative control; PTPN12, protein tyrosine phosphatase nonreceptor type 12; OE, overexpression; SD, standard deviation; STZ, streptozotocin.

The authors confirmed this error did not significantly affect either the results or the conclusions of the paper.

Click here to view the updated version of the article.

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References

1. Hu D, Tian Y, Ye L, et al. Transthyretin-induced increase in circ_0007411 represses neovascularization of human retinal microvascular endothelial cells in hyperglycemia via the miR-548m/PTPN12/SKP1/EGFR pathway. Ann Transl Med 2022;10:556. [Crossref] [PubMed]