Erratum: Myostatin is involved in skeletal muscle dysfunction in chronic obstructive pulmonary disease via Drp-1 mediated abnormal mitochondrial division

Erratum to: Ann Transl Med 2022;10:162.

The article (1) titled “Myostatin is involved in skeletal muscle dysfunction in chronic obstructive pulmonary disease via Drp-1 mediated abnormal mitochondrial division” (doi: 10.21037/atm-22-377) unfortunately contains errors in Figure 1. The images of Western blotting analysis of Myostatin, Drp-1 and GAPDH were mistakenly used. Correct Figure 1 is presented below. Figure 1’s legend is correct and unchanged.

Figure 1 in the original article:

Correct Figure 1:

Figure 1 Differences in Drp-1 and myostatin protein expression. C2C12 cells were transfected with myostatin siRNA, treated with 5% CSE for 12 hours, and the protein was then extracted. Drp-1 and myostatin were analyzed by Western blot. The transfected cells expressed less Drp-1 and myostatin than the un-transfected cells. They also expressed more Drp-1 and myostatin than the cells that did not undergo the CSE intervention. In this assay, Drp-1 had the same trend with the altered expression of myostatin. The above differences were statistically significant (P<0.05). CON, the control group; MS, the myostatin siRNA group; CSE, the 5% CSE group; MSC, the myostatin siRNA + 5% CSE group; Drp-1, dynamin-related protein 1; CSE, cigarette smoke extracts.

The authors confirmed the errors did not significantly affect either the results or the conclusions of the paper.

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References

1. Tan Z, Zhao M, Li J, et al. Myostatin is involved in skeletal muscle dysfunction in chronic obstructive pulmonary disease via Drp-1 mediated abnormal mitochondrial division. Ann Transl Med 2022;10:162. [Crossref] [PubMed]