Fertility preservation in young women with breast cancer: a narrative review of effectiveness, oncologic safety, and clinical practice implications

Breast cancer is the most frequently diagnosed malignancy among women of reproductive age, and advances in cancer survival have increased the relevance of fertility preservation (FP) as a component of comprehensive oncologic care. Concerns regarding treatment-related gonadotoxicity, potential delays in chemotherapy initiation, and long-term oncologic safety continue to influence clinical decision-making. This narrative review of systematic reviews aimed to synthesize contemporary evidence on FP methods in young women with breast cancer, focusing on effectiveness, timing, and oncologic safety.