Predicting aggressive behavior in small renal tumors prior to treatment

With widespread utilization of cross sectional imaging, the incidence of renal tumors continues to increase and tumors ≤4 cm comprise 48–66% of new renal cell carcinoma (RCC) diagnoses (1). The increased detection of small incidental tumors and technological improvements in surgery may lead to overtreatment of co-morbid patients with slow growing tumors (2).