Profiling changes in metabolism and the immune microenvironment in lung tumorigenesis

Lung cancer is the leading cause of cancer-related mortality worldwide, with 5-year survival rates still below 20% (1). Several multidisciplinary approaches are used clinically for the treatment of this disease. Depending on the type, classification, and staging of the lung tumor, patients are treated with surgery, radiotherapy, chemotherapy, or immunotherapy, alone or in combination.