The prognostic significance of preexisting diabetes in patients with surgically treated renal cell carcinoma: the ongoing debate

Because renal cell carcinoma (RCC) patients are likely to have substantial comorbidities due to advanced age at the time of diagnosis, it is important to explore the effects of preexisting medical diseases on survival after definitive surgical treatment (1). Several epidemiological studies have detected a significant association between RCC prognosis and metabolic syndrome components, such as obesity, hypertension, diabetes mellitus (DM), and dyslipidemia (2-5).