Combining old and new strategies for colorectal cancer screening

Colorectal cancer (CRC) is the third most common form of cancer, accounting for approximately 10% of all cancer- related deaths worldwide and accounting for as many as 19.1 million cause-specific disability-adjusted life years (DALYs) each year (1). The highest incidence rate is found in developed countries and seems prevalently associated with western lifestyle and dietary habits. However, the epidemiologic burden of CRC is raising also in other parts of the world, such as in Asia, where CRC incidence has increased by 2- to 4-fold during the past decade (1).