MicroRNA targeting energy metabolism in ovarian cancer: a potent contender for future therapeutics

The metabolic activities of cancer cells are frequently altered to sustain their malignant properties under the influence of oncogenes and tumor suppressors (1). Therefore, it is highly pertinent to determine the key regulators of metabolic reprogramming during tumor progression. MicroRNAs (miRNAs) are one such class of small non-coding RNA regulators that influence cellular processes during both physiological and pathological conditions. In recent years, the roles of miRNAs in association with energy metabolism have gained much interest in the field of cancer.