Two-stage revision surgery for periprosthetic joint infection following total hip arthroplasty

Total hip arthroplasty (THA) is a common, highly successful surgical intervention for the treatment of symptomatic degenerative conditions of the hip, such as osteoarthritis (1). Periprosthetic joint infection (PJI) is an uncommon, but potentially devastating complication of THA, with a reported incidence of between 0.6% and 2.2% (2-4). PJI often necessitates invasive treatment strategies, such as revision surgery, and has a significant negative impact on patients’ quality of life (5,6). With more than 1 million THAs performed worldwide each year, the health and economic burdens of this infective complication are substantial (1,3). Furthermore, two large national registry studies have demonstrated that the risk of revision due to hip PJI is rising (7,8). In this context, an understanding of the most effective treatment options is of great importance.