Review Article on Ovarian Cancer: State of the Art and Perspectives of Clinical Research Upfront debulking surgery for high-grade serous ovarian carcinoma: current evidence Orestis Tsonis, Fani Gkrozou, Konstantinos Vlachos, Minas Paschopoulos, Michail C. Mitsis, Nikolaos Zakynthinakis-Kyriakou, Stergios Boussios, George Pappas-Gogos Abstract stergios.boussios@nhs.net