Long-acting glucagon-like peptide-1 receptor agonist—status December 2018

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now included in most guidelines for treatment of type 2 diabetes, most recently in the Consensus Report by the European Society for the Study of Diabetes (EASD) and the American Diabetes Association (ADA) (1). However, it is still just a few percent of the diabetes patients that actually receive GLP-1 RA therapy. This is an interesting paradox which needs serious contemplation.