Rheumatologic Skin Disease

Posted On 2021-06-16 09:59:13

The content of the narrative reviews in this Series was designed to provide non-dermatologist readers with a better perspective on the value of clinical observation and translational research focused on the cutaneous manifestations of genetically-complex, environmentally-impacted and variably-expressed human illnesses such as the autoimmune connective tissue diseases.

Editorial on Rheumatologic Skin Disease
Why rheumatologic skin disease?
Richard D. Sontheimer, M. Kari Connolly, David F. Fiorentino, Victoria P. Werth

Review Article on Rheumatologic Skin Disease
Role of biomarkers in the diagnosis and prognosis of patients with cutaneous lupus erythematosus
Jane L. Zhu, Samantha M. Black, Benjamin F. Chong

Evaluating safety and compatibility of anti-tumor necrosis factor therapy in patients with connective tissue disorders
Jordan T. Said, Scott A. Elman, Joseph F. Merola

The CLASI, a validated tool for the evaluation of skin disease in lupus erythematosus: a narrative review
Srita Chakka, Rebecca L. Krain, Josef Symon S. Concha, Benjamin F. Chong, Joseph F. Merola, Victoria P. Werth

Dermatomyositis and malignancy: should all patients with dermatomyositis undergo malignancy screening?
Urmi Khanna, Fabrizio Galimberti, Yumeng Li, Anthony P. Fernandez

Dermatomyositis autoantibodies: how can we maximize utility?
Luqman Mushila Hodgkinson, Tiffany Tingshuen Wu, David Franklin Fiorentino

Environmental triggers of dermatomyositis: a narrative review
Christina E. Bax, Spandana Maddukuri, Adarsh Ravishankar, Lisa Pappas-Taffer, Victoria P. Werth

Polishing the crystal ball: mining multi-omics data in dermatomyositis
Rochelle L. Castillo, Alisa N. Femia

Covert clues: the non-hallmark cutaneous manifestations of dermatomyositis
Rochelle L. Castillo, Alisa N. Femia

Morphea: progress to date and the road ahead
Laila Abbas, Adrienne Joseph, Elaine Kunzler, Heidi T. Jacobe

Systemic sclerosis (scleroderma): remaining challenges
Mary Karin Connolly

Advances in cutaneous vasculitis research and clinical care
Avrom Caplan, Robert G. Micheletti

Human cutaneous B cells: what do we really know?
Irina Lerman, Drew C. Mitchell, Christopher T. Richardson

Pruritus in autoimmune connective tissue diseases
Hee Joo Kim

Abstract on Rheumatologic Skin Disease
AB001. Understanding transcriptional connections of chronic cutaneous lupus erythematosus between humans and animal models
Frane Banovic, Amanda Blubaugh, Tara Denley, Robert M. Gogal

AB002. Quality of life is inversely related to income in patients with cutaneous lupus
Smriti Prasad, Linda Hynan, Mary-Margaret Chren, Benjamin Chong

AB003. Increased CD69+ tissue-resident memory T cells and STAT3 expression in cutaneous lupus erythematosus patients recalcitrant to antimalarials
Majid Zeidi, Kristen L. Chen, Krisha Desai, Hee Joo Kim, Srita Chakka, Rachel Lim, Victoria P. Werth

AB004. Evaluating differences in meaningful change in disease activity between different races and clinical subtypes affected by cutaneous lupus erythematosus
Srita Chakka, Rebecca Krain, Sarah Ahmed, Josef Symon S. Concha, Victoria P. Werth

AB005. Assessing meaningful changes in disease activity as clinical trial clinical efficacy measures for cutaneous lupus erythematosus
Srita Chakka, Rebecca Krain, Sarah Ahmed, Josef Symon S. Concha, Rui Feng, Victoria P. Werth

AB006. A modular analysis approach to studying gene expression in cutaneous lupus erythematosus
Jane Zhu, Ly Tran, Frank Zheng, Judith James, Joel Guthridge, Benjamin Chong

AB007. Worse skin disease severity may distinguish patients who progress from cutaneous lupus erythematous to systemic lupus erythematous
Frances Walocko, Samantha Black, Scott Anderson, Xilong Li, Beverley Adams-Huet, Benjamin Chong

AB008. Utility of repeat latent tuberculosis testing in patients with immune-mediated diseases taking biologics
Urmi Khanna, Ariana Ellis, Josh Gallop, Abdulaziz Galadari, Jeffery Hu, Anthony P. Fernandez

AB009. Successful treatment of severe systemic lupus erythematosus and psoriasis with IL-17A inhibition
Danielle M. Robinett, Ilana Rosman, Louis Dehner, Deepali Sen, Heather Jones

AB010. Keloidal scleroderma with isolated intertriginous involvement
Vijay Balakrishnan, Lauren V. Graham, Lauren C. S. Kole

AB011. A Gottron’s papule mimicker: an unusual presentation of porokeratosis plantaris palmaris et disseminata
Elizabeth Schoenberg, Byron Ho, Linglei Ma, Inbal Sander

AB012. Clinical and demographic features of morphea patients with mucocutaneous involvement: a cross sectional study from the morphea of adults and children (MAC cohort)
Smriti Prasad, Samantha Black, Shivani Sharma, Heidi Jacobe

AB013. CXCL4-DNA immune complexes drive inflammation in systemic sclerosis by amplifying TLR9-mediated interferon-α production
Ernest Y. Lee, Roberto Lande, Carlo Chizzolini, Gerard C. L. Wong, Loredana Frasca

AB014. Developing classification criteria for skin-predominant dermatomyositis: assessing the methodology of the prospective validation study
Josef Symon S. Concha, Joseph F. Merola, David Fiorentino, Jan Peter Dutz, Mark Goodfield, Filippa Nyberg, Beatrix Volc-Platzer, Manubo Fujimoto, Chia Chun Ang, Victoria P. Werth

AB015. Skin disease activity and autoantibody phenotype are major determinants of blood interferon signatures in dermatomyositis
Mika Tabata, Kavita Sarin, Nareh Marukian, Karen Page, Christine Huard, Shanrong Zhao, Donald Bennett, Jillian Johnson, Kristen Johnson, David Fiorentino

AB016. A double-blind, placebo-controlled, phase 2 trial of a novel toll-like receptor 7/8/9 antagonist (IMO-8400) in dermatomyositis
Yoo Jung Kim, Elena Schiopu, Katalin Dankó, Tahseen Mozaffar, Srinivas Chunduru, Kirstin Lees, Namita Goyal, Jeffrey Sarazin, David F. Fiorentino, Kavita Y. Sarin

AB017. Increased dendritic cells and IFN-beta and MxA protein expression in spongiotic dermatitis differentiates dermatomyositis from eczema
Majid Zeidi, Kristen L. Chen, Basil Patel, Rachel Lim, Victoria P. Werth

AB018. Myeloid dendritic cells (mDCs) are major producers of interferon-beta in dermatomyositis and increased numbers of mDCs are found in hydroxychloroquine nonresponders
Kristen L. Chen, Majid Zeidi, Maria Wysocka, Nithin Reddy, Arvin Jadoo, Muhammad M. Bashir, Sarah Ahmed, Basil Patel, Kevin K. Zhang, Barbara White, Victoria P. Werth

AB019. Response to tofacitinib in a case of refractory TIF-1 positive amyopathic dermatomyositis with arthritis
Sion Ward Jasmine, Deepali Sen, Heather Anna Jones

AB020. A case report on cutaneous necrotizing vasculitis treated with colchicine in a Filipino adult male
Luisa Marie S. Cruz, Rogelio G. Balagat, Martha B. Tapales

AB021. Comparing the performance of two interferon-gamma release assays in autoimmune skin disease patients: a prospective study
Rebecca L. Krain, Rebecca G. Gaffney, Emily R. Keyes, Rui Feng, Victoria P. Werth

AB022. Biologics and vaccination: relationship of influenza, pneumonia and zoster
Deep Patel, Steven Maczuga, Matthew Helm, Galen Foulke

AB023. An atypical clinical presentation of alopecia in two patients with systemic lupus erythematosus
Irina Lerman, Ritesh Agnihothri, Glynis A. Scott, Christopher T. Richardson

AB024. A case of bullous systemic lupus erythematosus confined to the oral mucosa
Jennifer Strunck, Lynne Morrison, Teri Greiling

AB025. Acute arthritis with dermatitis: a case of multicentric reticulohistiocytosis
Omid Zahedi Niaki, Nicole Gunesekera, Christine Lian, Ruth Ann Vleugels, Deborah A. Scott

The series “Rheumatologic Skin Disease” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding. Richard D. Sontheimer, M. Kari Connolly, David Fiorentino and Dr. Victoria Werth served as the unpaid Guest Editors for the series.