Novel Tools and Therapies for Ocular Regeneration

Posted On 2021-08-19 13:44:21

This special series is very timely since there has been a recent increase in the momentum of translational research in ocular regeneration. This increase stems partially from the success of ocular gene therapy. This special eye series includes review and original articles of novel tools and therapies being developed for ocular regeneration. The goal of this eye series is to provide some overview of the latest research being done in the area of ocular regeneration in order to highlight the broad potential in this field.

Advantages of ocular regeneration research
Susanna S. Park

Review Article
In vivo retinal imaging in translational regenerative research
Ifat Sher, Daniel Moverman, Hadas Ketter-Katz, Elad Moisseiev, Ygal Rotenstreich

Toward a clinical optoretinogram: a review of noninvasive, optical tests of retinal neural function
Ravi S. Jonnal

Animal models of corneal endothelial dysfunction to facilitate development of novel therapies
Sangwan Park, Brian C. Leonard, Vijay Krishna Raghunathan, Soohyun Kim, Jennifer Y. Li, Mark J. Mannis, Christopher J. Murphy, Sara M. Thomasy

Animal models of diabetic retinopathy
Jose Quiroz, Amirfarbod Yazdanyar

Original Article
Analysis of the retinal capillary plexus layers in a murine model with diabetic retinopathy: effect of intravitreal injection of human CD34+ bone marrow stem cells
Kong Wa Cheung, Amirfarbod Yazdanyar, Christian Dolf, Whitney Cary, Nicholas Marsh-Armstrong, Jan A. Nolta, Susanna S. Park

Retinal degeneration in mice and humans with neuronal ceroid lipofuscinosis type 8
Elyse M. Salpeter, Brian C. Leonard, Antonio J. Lopez, Christopher J. Murphy, Sara Thomasy, Denise M. Imai, Kristin Grimsrud, K. C. Kent Lloyd, Jiong Yan, Rossana Sanchez Russo, Suma P. Shankar, Ala Moshiri

Subretinal versus intravitreal administration of human CD34+ bone marrow-derived stem cells in a rat model of inherited retinal degeneration
Un Chul Park, Susanna S. Park, Bo Hee Kim, Sung Wook Park, Young Joo Kim, Whitney Cary, Johnathon D. Anderson, Jan A. Nolta, Hyeong Gon Yu

Review Article
The basic science of optic nerve regeneration
Lindsay Fague, Yin Allison Liu, Nicholas Marsh-Armstrong

Targeting vascular endothelial growth factor using retinal gene therapy
Sook H. Chung, Sonia L. Frick, Glenn Yiu

Gene therapy for inherited retinal diseases
Yan Nuzbrokh, Sara D. Ragi, Stephen H. Tsang

Pluripotent stem cell therapy for retinal diseases
Ishrat Ahmed, Robert J. Johnston Jr, Mandeep S. Singh

MicroRNA and diabetic retinopathy—biomarkers and novel therapeutics
Zeljka Smit-McBride, Lawrence S. Morse

The focused issue “Novel Tools and Therapies for Ocular Regeneration” was commissioned by the editorial office, Annals of Translational Medicine without any sponsorship or funding. Susanna S. Park is serving as the unpaid Guest Editor for the focused issue.