In 2024, ATM reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.
Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.
January, 2024
Elisa Belluzzi, University of Padova, Italy
February, 2024
John Maher, King's College London, UK
March, 2024
Robert W Keane, University of Miami, USA
May, 2024
Heather A Hartman, University of Michigan, USA
July, 2024
Connor Wakefield, University of Nevada Las Vegas, USA
August, 2024
Michael R. Shurin, University of Pittsburgh Medical Center, USA
October, 2024
Ibrahim Kamel, Boston University, USA
January, 2024
Elisa Belluzzi
Elisa Belluzzi is a molecular biologist with a PhD in biotechnologies. She is currently Assistant Professor at the Musculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova. Her main research interests focus on musculoskeletal diseases, in particular osteoarthritis and bone cancer. Her studies are devoted on the characterization of the different OA joint tissues and on the identification of disease biomarkers. Moreover, she is actively involved in clinical studies. Connect with her on LinkedIn or learn more about her here.
In Dr. Belluzzi’s opinion, peer review is essential as it ensures the quality, accuracy, and credibility of academic research. Furthermore, she believes that every researcher should be engaged as a reviewer. Unfortunately, the reviewer does not receive recognition often, but his/her role is fundamental for the publication of high-quality articles.
Biases are inevitable in peer review and reviewers should be aware of their existence. Dr. Belluzzi thinks that the journals should set guidelines for the reviewers explaining the potential biases and how to deal with them. Knowing the various types of biases can help the reviewer to recognize them and thus minimize their influence during the review process. Moreover, she thinks that the journals should give recognition and incentives for those reviewers that provide high-quality reviews. This would encourage more people to be engaged in peer review and pay attention to biases. In addition, the opinion of more than one reviewer should be requested to reduce the risk of bias.
When Dr. Belluzzi reviews a manuscript, she reads it as if she was a reader and tries to understand if: i) the manuscript is clear; ii) the topic is of interest; iii) something is missing to be able to replicate the data; iv) the weak points are discussed; v) ethical committee approval is reported and vi) the statistical analysis is appropriate. She tries her best to give a useful and constructive feedback to the authors in order to improve the quality of the manuscript.
From a reviewer’s point of view, Dr. Belluzzi considers data sharing a crucial point in science. In particular, it is important to allow the data’s reproducibility, to enable further analysis promoting scientific development and discovery. The reviewer has a great responsibility in this context. Indeed, the reviewer should check whether authors have made the data available to readers.
(by Lareina Lim, Brad Li)
February, 2024
John Maher
Dr. John Maher is the scientific founder and chief scientific officer of Leucid Bio. He is also a clinical immunologist who leads the "CAR Mechanics" research group within King's College London. He played a key role in the early development of second generation (CD28) CAR technology while a visiting fellow at Memorial Sloan Kettering Cancer Center, an approach that has achieved clinical impact in haematological malignancies. His research is focused on the development of adoptive immunotherapy using CAR engineered and gamma delta T-cells, with a primary emphasis on solid tumour types. In addition, he is a consultant immunologist at Eastbourne Hospital. Connect with him on LinkedIn.
In Dr. Maher’s opinion, peer review should be honest, objective and informed, leading to the improvement of the quality of a manuscript without being destructive. Reviewers should have relevant expertise and be free of conflicts of interest in respect of the submitted manuscript.
According to Dr. Maher, ultimately peer review is conducted by humans who work in a closely related area of research so it is unsurprising that bias will occur. This emphasizes the key role of the editor in assessing the merits of comments raised by reviewers during the peer-review process.
“Annals of Translational Medicine is a respected journal which publishes high-quality content of direct relevance to my work on CAR T-cell immunotherapy,” says Dr. Maher.
(by Lareina Lim, Brad Li)
March, 2024
Robert W Keane
Dr. Robert W Keane is Professor of Physiology and Biophysics, Neurological Surgery and Microbiology and Immunology at the University of Miami, Miller School of Medicine. Over the last 30 years, his research has focused on understanding the innate immune response in the central nervous system. Dr. Keane is the discoverer of inflammasomes in neurons after central nervous system injury. He received a fast-track STTR grant from the National Institutes of Health to develop a biologic to treat central nervous system injury, and has published extensively in fields of neuroinflammation and neuroimmunology. He is a founding member of InflamaCORE, LLC, a company dedicated to treating and diagnosing inflammatory injury and disease. Learn more about him here.
Dr. Keane thinks that peer review is needed to evaluate the validity, quality and originality of articles for publication. Its helps maintain integrity in science by weeding out poor-quality articles. Peer review also improves the quality of manuscripts that are accepted for publication and determines whether the article is sufficiently novel and warrants publication.
In Dr. Keane’s opinion, a healthy peer-review system should contain fairness of critical analysis of manuscripts; the selection of appropriate reviewers with relevant expertise; identifiable, publicly accountable reviewers; timely reviews, and helpful critical commentary.
(by Lareina Lim, Brad Li)
May, 2024
Heather A Hartman
Dr. Heather Hartman, MD, is a clinical instructor in the Department of Surgery and a post-doctoral fellow at the Institute for firearm injury prevention at the University of Michigan. After earning a medical degree at Sidney Kimmel Medical College at Thomas Jefferson University, she completed her general surgery residency at Temple University Hospital. During the academic time in her residency, she pursued research in fetal therapies including fetal gene editing. Next, she trained in pediatric surgical critical care at the University of Michigan. She is resuming her surgical training as a pediatric surgery fellow at Nemours Children’s Hospital in Delaware this year. Currently, her main areas of research include hospital-based violence prevention programs, secure storage of firearms in families with children, and management of pediatric trauma.
During Dr. Hartman’s research career, she thinks that spanning benchtop science to clinical-based trials, she has gained a deep appreciation for the value of the review process. As a researcher, the inquiries from reviewers and editors have often helped to refine her analysis and bring further clarity to an area of interest. Often, authors become so deeply knowledgeable about their topic that it becomes difficult to see where an item needs further explanation or an analysis could be re-worked to have an even more powerful impact. Even when reviewers may not fully agree with the study, the insightful questions and suggestions of reviewers allow for further refining of manuscripts so that high-quality research may be published.
“To ensure the integrity of research, a clearly written methods section is vital,” Dr. Hartman says. As a researcher, Dr. Hartman will often use the methods section of prior works to guide the design process for new projects, so it is critical to include all relevant methods, which may require an online supplement. The review process is also important for ensuring that the limitations of the research, not just the strengths, be clearly identified, including which specific populations the research does and does not apply to. Similarly, any funding sources, including grants, and potential conflicts of interest should be disclosed.
As a reviewer, Dr. Hartman strives to give constructive feedback, pointing out areas where perhaps something could be re-worded to be clearer or an analysis could be expanded to strengthen the manuscript. While reviewers may not always agree with the design and purpose of a manuscript, it is important to remember that there is another person(s) who spent considerable time and effort with this study and that feedback should be framed in a positive, constructive manner.
“Time management is critical. Being a reviewer is not a laborious process, usually just thirty minutes to an hour, but, out of respect to the authors and the journal, it must be completed in a timely manner. I only accept invitations to review when I know I have the time to commit. Often, reviewer comments can be accomplished in a brief paragraph, although on occasion a more detailed response may be warranted,” says Dr. Hartman.
(by Lareina Lim, Brad Li)
July, 2024
Connor Wakefield
Dr. Wakefield received his M.D. from Rush Medical College and is a graduate of the Internal Medicine Residency of San Antonio Uniformed Services Health Education Consortium (SAUSHEC). He is currently a Fellow Physician in Pulmonary/Critical Care Medicine at the University of Nevada Las Vegas. He has robust experience in clinical research and has published approximately 30 peer-reviewed publications. Current ongoing research interests include critical care clinical outcomes research, development of blood-based biomarkers as screening modality for solid malignancy, and role of sarcopenia on outcomes of various disease processes.
Dr. Wakefield believes reviewing scientific work is one of the pillars of medicine, to partake in a lifelong effort to continually educate oneself. Reviewers should ultimately have a strong passion for participating in the research process with reviewing other’s research. Specific qualities reviewers should strive to hold include attention to detail, unbiased perceptions of others, and adherence to scientific research principles.
According to Dr. Wakefield, an integral concept in the research process is to be able to replicate other’s work to demonstrate continued significance and improve on those previously. Data sharing may enable the ability to replicate other’s research processes and provide a more insightful analysis. Furthermore, this may also provide for novel ad hoc analysis with future applications which could be very beneficial to the scientific community.
“Although I have found life only gets busier as I have advanced through my career and education, I have made it a point to engage in clinical research activities on a consistent basis. Peer review allows me to view research from a different lens and to have an appreciation of varied backgrounds and research methods. I try to consistently make an effort to always review articles on a routine basis to maintain this goal,” says Dr. Wakefield.
(by Lareina Lim, Brad Li)
August, 2024
Michael R. Shurin
After graduating from Moscow State Medical School in 1984, Michael R. Shurin, MD, PhD, D(ABMLI), got the postgraduation training in clinical biochemistry and clinical immunology, and obtained his PhD degree in Immunopharmacology in 1991. He joined the faculty of the Department of Pathology at the University of Pittsburgh Medical Center in 1991 where he is a Professor of Pathology and Immunology and a Medical Director of the Division of Clinical Immunopathology. His main research interests are in the tumor immunoenvironment and solid tumor innervation. Prof. Shurin is an author of more than 250 peer-reviewed publications and numerous reviews, an editor of several books, including Dendritic Cell in Cancer, Infection and Cancer and The Tumor Immunoenvironment, and an organizer of several popular international conferences on Immune-Mediated Diseases, Immunodiagnostics and Immunomonitoring and Cancer Immunotherapy. He is a member of several grant review and editorial boards and many clinical and research societies.
ATM: What role does peer review play in science?
Prof. Shurin: Behind every submitted manuscript, someone awaits decision. Often this decision may change professional career, funding opportunity, research position or direction of future experimental studies. At the same time, acceptance of inappropriately developed manuscripts, uncompleted studies or mistaken experimental work may form misleading and unsuitable impression about science in young investigators. This may also delay or prevent formation of analytical thinking, research mentality and appreciation of hard work and research ethic. Thus, I think that manuscript review process and reviewers are responsible for the formation and polishing of the next generation scientists.
ATM: What do you regard as a constructive/destructive review?
Prof. Shurin: I have received and prepared hundreds of reviews and can tell you that the reviewers and the authors usually have different opinions about constructive and destructive comments in a review. I think that this is a tricky question… Being a reviewer for more than three decades, I can tell you that some manuscripts should be destructed and never be born. At the same time, often I disagree with other reviewers being either too tough or too soft on their comments and suggestions. There are no acceptable rules and we all learn by our own mistakes.
ATM: The burden of being a scientist/doctor is heavy. How do you allocate time to do peer review?
Prof. Shurin: There is no extra time between clinical duties, research lab and family/house responsibilities. My only rule for manuscript review is to do it right away or do not accept. If I do not follow this rule, I might have tens of unfinished and delayed reviews mixed with tens of other incomplete writings; and all of these stuffed by other ongoing projects.
(by Lareina Lim, Brad Li)
October, 2024
Ibrahim Kamel
Ibrahim Kamel, MD, MHA, is a Clinical Instructor at Boston University Chobanian & Avedisian School of Medicine and a Clinical Associate at Tufts School of Medicine. He is a resident in Internal Medicine at St. Elizabeth Medical Center in Boston, with prior training at Carney Hospital. Dr. Kamel’s research focuses on cardiovascular medicine, artificial intelligence applications in healthcare, and reducing health disparities. His recent projects include AI-driven ECG analysis for detecting myocardial infarctions and the impact of heart failure education on patient readmissions. He has contributed extensively to peer-reviewed publications, addressing topics such as coronary microvascular dysfunction, critical care disparities, and stem cell therapy in heart failure. Connect with him on LinkedIn.
According to Dr. Kamel, a healthy peer-review system ensures transparency, fairness, and constructive feedback. It promotes rigorous evaluation, acknowledges expertise, and minimizes bias while maintaining confidentiality.
Speaking of the limitations of the existing peer-review system, Dr. Kamel reckons that they include reviewer bias, lack of transparency, and delays in the review process. To improve it, integrating open peer review, providing adequate training for reviewers, and incentivizing participation through recognition or compensation could make the system more effective.
“Peer reviewing is an opportunity to contribute to scientific progress, uphold research integrity, and stay updated on emerging trends. The intrinsic satisfaction of fostering knowledge and supporting colleagues in their academic journey is highly motivating,” says Dr. Kamel.
(by Lareina Lim, Brad Li)
