Most Read article list (ranking real-time pageviews since the publication of the article)

  
Review Article
Paradigms lost—an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis
Astrid O. Leech, Rodrigo G.B. Cruz, Arnold D.K. Hill, Ann M. Hopkins
Published online: 15 August 2015
Original Article
Differential diagnosis of thalassemia and iron deficiency anemia in pregnant women using new formulas from multidimensional analysis of red blood cells
Haijun Xiao, Yidan Wang, Yi Ye, Chen Yang, Xiaolong Wu, Xiurong Wu, Xiaomei Zhang, Tianxi Li, Jianping Xiao, Ling Zhuang, Huan Qi, Feng Wang
Published online: 30 January 2021
Review Article
Oropharyngeal colonization: epidemiology, treatment and ventilator-associated pneumonia prevention
Jonathan Messika, Béatrice La Combe, Jean-Damien Ricard
Published online: 13 November 2018
Perspective
RNAs that make a heart beat
Mithun Mitra, Hilary A. Coller
Published online: 19 December 2016
Review Article
Prognostic biomarkers in acute coronary syndrome
Gian Luca Salvagno, Chiara Pavan
Published online: 15 July 2016
Review Article on Toward Precision Medicine in Neurological Diseases
Toward precision medicine in amyotrophic lateral sclerosis
Zhang-Yu Zou, Chang-Yun Liu, Chun-Hui Che, Hua-Pin Huang
Published online: 27 January 2016
Original Article
Efficacy and safety of antibiotic agents in children with COVID-19: a rapid review
Jianjian Wang, Yuyi Tang, Yanfang Ma, Qi Zhou, Weiguo Li, Muna Baskota, Yinmei Yang, Xingmei Wang, Qingyuan Li, Xufei Luo, Toshio Fukuoka, Hyeong Sik Ahn, Myeong Soo Lee, Zhengxiu Luo, Enmei Liu, Yaolong Chen, on behalf of COVID-19 Evidence and Recommendations Working Group
Published online: 29 May 2020
Original Article
Prevalence of cervical spine degenerative changes in elderly population and its weak association with aging, neck pain, and osteoporosis
Xiao-Rong Wang, Timothy C. Y. Kwok, James F. Griffith, Blanche Wai Man Yu, Jason C. S. Leung, Yì Xiáng J. Wáng
Published online: 30 September 2019
Review Article on Medical Artificial Intelligent Research
Using artificial intelligence to improve medical services in China
Ruiyang Li, Yahan Yang, Shaolong Wu, Kai Huang, Weirong Chen, Yizhi Liu, Haotian Lin
Published online: 15 June 2020
Review Article on Health and Medicine: a new era
Inflammation, immunosuppressive microenvironment and breast cancer: opportunities for cancer prevention and therapy
Sachin Kumar Deshmukh, Sanjeev Kumar Srivastava, Teja Poosarla, Donna Lynn Dyess, Nicolette Paolaungthong Holliday, Ajay Pratap Singh, Seema Singh
Published online: 31 October 2019
Review Article
The role of genetics and antibodies in sepsis
Evangelos J. Giamarellos-Bourboulis, Steven M. Opal
Published online: 13 September 2016
Review Article
Asian-Indians: a review of coronary artery disease in this understudied cohort in the United States
Devarshi R. Ardeshna, Tamunoinemi Bob-Manuel, Amit Nanda, Arindam Sharma, William Paul Skelton IV, Michelle Skelton, Rami N. Khouzam
Published online: 15 January 2018
Review Article on Mesothelioma
Diagnosis and prognosis—review of biomarkers for mesothelioma
Huan H. Sun, Allen Vaynblat, Harvey I. Pass
Published online: 15 June 2017
Review Article
The combination of checkpoint immunotherapy and targeted therapy in cancer
Niki Karachaliou, Maria Gonzalez Cao, Aaron Sosa, Jordi Berenguer, Jillian Wilhelmina Paulina Bracht, Masaoki Ito, Rafael Rosell
Published online: 28 September 2017
Review Article
Beyond PD-L1 testing-emerging biomarkers for immunotherapy in non-small cell lung cancer
Khinh Ranh Voong, Josephine Feliciano, Daniel Becker, Benjamin Levy
Published online: 19 September 2017
Review Article
Mechanisms involved in brain dysfunction in mechanically ventilated critically ill patients: implications and therapeutics
Marc Turon, Sol Fernández- Gonzalo, Candelaria de Haro, Rudys Magrans, Josefina López- Aguilar, Lluís Blanch
Published online: 25 January 2018
Guideline
Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)
Jun Guo, Shukui Qin, Jun Liang, Tongyu Lin, Lu Si, Xiaohong Chen, Zhihong Chi, Chuanliang Cui, Nan Du, Yun Fan, Kangsheng Gu, Fang Li, Junling Li, Yongheng Li, Houjie Liang, Jiwei Liu, Man Lu, Aiping Lu, Kejun Nan, Xiaohui Niu, Hongming Pan, Guoxin Ren, Xiubao Ren, Yongqian Shu, Xin Song, Min Tao, Baocheng Wang, Wenbin Wei, Di Wu, Lingying Wu, Aiwen Wu, Xiaolin Xu, Junyi Zhang, Xiaoshi Zhang, Yiping Zhang, Huiyan Zhu, written on behalf of Chinese Society of Clinical Oncology (CSCO) Melanoma Panel
Published online: 17 December 2015
Review Article on Inborn Errors of Metabolism
Amino acid disorders
Ermal Aliu, Shibani Kanungo, Georgianne L. Arnold
Published online: 29 December 2018
Review Article on Mesothelioma
Extrapleural pneumonectomy (EPP) vs. pleurectomy decortication (P/D)
Hasan Fevzi Batirel
Published online: 15 June 2017
Review Article
Predictive factors for immunotherapy in melanoma
Cristina Teixidó, Maria González-Cao, Niki Karachaliou, Rafael Rosell
Published online: 14 September 2015
Review Article
PD-L1 assessment in urothelial carcinoma: a practical approach
Markus Eckstein, Alessia Cimadamore, Arndt Hartmann, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli, Rodolfo Montironi, Thomas Gevaert
Published online: 29 November 2019
Perspective
Scoring systems for the characterization of sepsis and associated outcomes
Natalie McLymont, Guy W. Glover
Published online: 29 December 2016
Original Article
Low serum IgG4 level: a potential diagnostic biomarker for IgA nephropathy
Xinyu Tian, Zhuan Cui, Song Wang, Yuejuan Pan, Lata A, Xinxin Chen, Xiaoxiao Wang, Xiaoyan Qiu, Zhenling Deng, Yue Wang
Published online: 15 May 2021
Review Article
Niemann-Pick disease treatment: a systematic review of clinical trials
Alejandro Santos-Lozano, Diana Villamandos García, Fabian Sanchis-Gomar, Carmen Fiuza-Luces, Helios Pareja-Galeano, Nuria Garatachea, Gisela Nogales Gadea, Alejandro Lucia
Published online: 23 December 2015
Focus on State of the Art in Diagnostics of the Acute Coronary Syndrome
The relationship between ABO blood group and cardiovascular disease: results from the Cardiorisk program
Enrico Capuzzo, Carlo Bonfanti, Francesco Frattini, Paolo Montorsi, Rosalia Turdo, Maria Grazia Previdi, Elisa Turrini, Massimo Franchini
Published online: 25 May 2016
Original Article
Hyaluronan expression in primary and secondary brain tumors
Laurence Jadin, Sandra Pastorino, Rebecca Symons, Natsuko Nomura, Ping Jiang, Tiffany Juarez, Milan Makale, Santosh Kesari
Published online: 21 April 2015
Review Article
Recruitment maneuvers in acute respiratory distress syndrome
Jean-Michel Constantin, Thomas Godet, Matthieu Jabaudon, Jean-Etienne Bazin, Emmanuel Futier
Published online: 25 July 2017
Review Article
Epidemiologic trends of sepsis in western countries
Alejandro Suarez De La Rica, Fernando Gilsanz, Emilio Maseda
Published online: 13 September 2016
Review Article
Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance
Anna Martinez-Cardús, Miguel Vizoso, Sebastian Moran, Jose Luis Manzano
Published online: 14 September 2015
Original Article
Elevated d-dimer cut-off values for computed tomography pulmonary angiography—d-dimer correlates with location of embolism
Mateuzs Piotr Kubak, Peter Mæhre Lauritzen, Arne Borthne, Espen Asak Ruud, Haseem Ashraf
Published online: 14 June 2016
Review Article
The critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review
Meng Liu, Xiao-Yu Kong, Yuan Yao, Xin-An Wang, Wei Yang, Hui Wu, Song Li, Jia-Wang Ding, Jian Yang
Published online: 31 March 2022
Review Article on Recent Developments in Cataract Surgery
Recent developments in the management of congenital cataract
Dominique Bremond-Gignac, Alejandra Daruich, Matthieu P. Robert, Sophie Valleix
Published online: 30 November 2020
Review Article on Innovations and Technology in Surgery
An update and review of cell-based wound dressings and their integration into clinical practice
Austin Pourmoussa, Daniel J. Gardner, Maxwell B. Johnson, Alex K. Wong
Published online: 19 December 2016
Editorial
Safe anticoagulation when heart and lungs are “on vacation”
Marina A. Dobrovolskaia, Scott E. McNeil
Published online: 15 May 2015
Big-data Clinical Trial Column
Variable selection in Logistic regression model with genetic algorithm
Zhongheng Zhang, Victor Trevino, Sayed Shahabuddin Hoseini, Smaranda Belciug, Arumugam Manivanna Boopathi, Ping Zhang, Florin Gorunescu, Velappan Subha, Songshi Dai
Published online: 02 February 2018
Review Article on Molecular Biomechanics
Molecular mechanisms of mechanotransduction in psoriasis
Lina S. Malakou, Antonios N. Gargalionis, Christina Piperi, Evangelia Papadavid, Athanasios G. Papavassiliou, Efthimia K. Basdra
Published online: 30 June 2018
Review Article on Capsule Endoscopy
Where do I see minimally invasive endoscopy in 2020: clock is ticking
Rami Eliakim
Published online: 13 May 2017
Surgical Technique
Use of distal perfusion in peripheral extracorporeal membrane oxygenation
George Makdisi, Tony Makdisi, I-Wen Wang
Published online: 15 March 2017
Original Article
Chemically defined serum-free and xeno-free media for multiple cell lineages
Sümeyra Naz Usta, Christopher D. Scharer, Jie Xu, Teryl K. Frey, Rodney J. Nash
Published online: 21 October 2014
Review Article
Right heart function during acute respiratory distress syndrome
Xavier Repessé, Antoine Vieillard-Baron
Published online: 25 July 2017
Review Article
Coronavirus disease 2019 (COVID-19): the portrait of a perfect storm
Giuseppe Lippi, Fabian Sanchis-Gomar, Brandon M. Henry
Published online: 16 April 2020
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