Most Read article list (ranking real-time pageviews since the publication of the article)

Jia Zhang, Zehua Bian, Guoying Jin, Yuhang Liu, Min Li, Surui Yao, Jing Zhao, Yuyang Feng, Xue Wang, Yuan Yin, Bojian Fei, Xiaofeng Han, Zhaohui Huang

Published online: 15 May 2019

PDF Pages: 198 Full Text (14566) Open Access

Review Article

Assessing breathing effort in mechanical ventilation: physiology and clinical implications

Heder de Vries, Annemijn Jonkman, Zhong-Hua Shi, Angélique Spoelstra-de Man, Leo Heunks

Published online: 15 October 2018

PDF Pages: 387 Full Text (14430) Open Access

Review Article

Melanoma: oncogenic drivers and the immune system

Niki Karachaliou, Sara Pilotto, Cristina Teixidó, Santiago Viteri, Maria Gonzalez-Cao, Aldo Riso, Daniela Morales-Espinosa, Miguel Angel Molina, Imane Chaib, Mariacarmela Santarpia, Eduardo Richardet, Emilio Bria, Rafael Rosell

Published online: 30 October 2015

PDF Pages: 265 Full Text (14308) Open Access

Original Article

Relationship between serum CA19-9 and CEA levels and prognosis of pancreatic cancer

Lei Wu, Peijun Huang, Fang Wang, Daqian Li, Erfu Xie, Yan Zhang, Shiyang Pan

Published online: 17 December 2015

PDF Pages: 328 Full Text (14367) Open Access

Review Article

The emerging role of immunotherapy in head and neck squamous cell carcinoma (HNSCC): anti-tumor immunity and clinical applications

Panagiota Economopoulou, Christos Perisanidis, Evaggelos I. Giotakis, Amanda Psyrri

Published online: 17 May 2016

PDF Pages: 173 Full Text (14275) Open Access

Editorial

Radiation therapy and the abscopal effect: a concept comes of age

John Ng, Tong Dai

Published online: 25 March 2016

PDF Pages: 118 Full Text (14162) Open Access

Review Article

Recent advances in the treatment of melanoma with BRAF and MEK inhibitors

Eva Muñoz-Couselo, Jesús Soberino García, José Manuel Pérez-García, Vanesa Ortega Cebrián, Javier Cortés Castán

Published online: 14 September 2015

PDF Pages: 207 Full Text (14122) Open Access

Review Article

Accuracy of non-invasive and minimally invasive hemodynamic monitoring: where do we stand?

Issa Pour-Ghaz, Theodore Manolukas, Nathalie Foray, Joel Raja, Aranyak Rawal, Uzoma N. Ibebuogu, Rami N. Khouzam

Published online: 11 September 2019

PDF Pages: 421 Full Text (14177) Open Access

Review Article

Transpulmonary pressure: importance and limits

Domenico Luca Grieco, Lu Chen, Laurent Brochard

Published online: 25 July 2017

PDF Pages: 285 Full Text (14182) Open Access

Review Article

Clinical manifestations of Wilson disease in organs other than the liver and brain

Karolina Dzieżyc-Jaworska, Tomasz Litwin, Anna Członkowska

Published online: 30 April 2019

PDF Pages: S62 Full Text (14101) Open Access

Review Article

Dead space in acute respiratory distress syndrome

Massimo Ferluga, Umberto Lucangelo, Lluis Blanch

Published online: 15 October 2018

PDF Pages: 388 Full Text (13893) Open Access

Review Article

Role of spironolactone in the treatment of heart failure with preserved ejection fraction

Constantine E. Kosmas, Delia Silverio, Andreas Sourlas, Peter D. Montan, Eliscer Guzman

Published online: 07 December 2018

PDF Pages: 461 Full Text (13834) Open Access

Theme Section: Pneumothorax

Pacemaker insertion

Maria Kotsakou, Ioannis Kioumis, George Lazaridis, Georgia Pitsiou, Sofia Lampaki, Antonis Papaiwannou, Anastasia Karavergou, Kosmas Tsakiridis, Nikolaos Katsikogiannis, Ilias Karapantzos, Chrysanthi Karapantzou, Sofia Baka, Ioannis Mpoukovinas, Vasilis Karavasilis, Aggeliki Rapti, Georgia Trakada, Athanasios Zissimopoulos, Konstantinos Zarogoulidis, Paul Zarogoulidis

Published online: 10 March 2015

PDF Pages: 42 Full Text (13808) Open Access

Original Article

Public health education for parents during the outbreak of COVID-19: a rapid review

Weiguo Li, Jing Liao, Qinyuan Li, Muna Baskota, Xingmei Wang, Yuyi Tang, Qi Zhou, Xiaoqing Wang, Xufei Luo, Yanfang Ma, Toshio Fukuoka, Hyeong Sik Ahn, Myeong Soo Lee, Yaolong Chen, Zhengxiu Luo, Enmei Liu, on behalf of COVID-19 Evidence and Recommendations Working Group

Published online: 29 May 2020

PDF Pages: 628 Full Text (13718) Reporting Checklist COI Form Open Access

Review Article

Effects of hypercapnia in acute respiratory distress syndrome

Nicolás Nin, Martín Angulo, Arturo Briva

Published online: 25 January 2018

PDF Pages: 37 Full Text (13648) Open Access

Review Article

Positive end-expiratory pressure: how to set it at the individual level

Luciano Gattinoni, Francesca Collino, Giorgia Maiolo, Francesca Rapetti, Federica Romitti, Tommaso Tonetti, Francesco Vasques, Michael Quintel

Published online: 25 July 2017

PDF Pages: 288 Full Text (13690) Open Access

Highlighted Reports in Galectins

Role of galectins in re-epithelialization of wounds

Noorjahan Panjwani

Published online: 20 September 2014

PDF Pages: 89 Full Text (13571) Open Access

Review Article

CTC enumeration and characterization: moving toward personalized medicine

Angela Toss, Zhaomei Mu, Sandra Fernandez, Massimo Cristofanilli

Published online: 26 November 2014

PDF Pages: 108 Full Text (13447) Open Access

Review Articles on Treatment for Hepatitis B

Treatment for hepatitis B in patients with drug resistance

Frank Tacke, Daniela C. Kroy

Published online: 27 September 2016

PDF Pages: 334 Full Text (13467) Open Access

Review Articles

Vitamin D and GI cancers: shedding some light on dark diseases

Laura Hargrove, Taylor Francis, Heather Francis

Published online: 25 December 2013

PDF Pages: 9 Full Text (13381) Open Access

Original Article

Comparative study of tumor markers in patients with colorectal carcinoma before and after chemotherapy

Atreyee Basu, Shashi Seth, Ashok K. Chauhan, Nupur Bansal, Kanchan Arora, Anuradha Mahaur

Published online: 29 February 2016

PDF Pages: 71 Full Text (13310) Open Access

Review Article

MR imaging for acute pancreatitis: the current status of clinical applications

Huan Sun, Hou-Dong Zuo, Qiao Lin, Dan-Dan Yang, Ting Zhou, Meng-Yue Tang, Yì Xiáng J. Wáng, Xiao-Ming Zhang

Published online: 26 June 2019

PDF Pages: 269 Full Text (13231) Open Access

Big-data Clinical Trial Column

%ggBaseline: a SAS macro for analyzing and reporting baseline characteristics automatically in medical research

Hong-Qiu Gu, Dao-Ji Li, Chelsea Liu, Zhen-Zhen Rao

Published online: 30 August 2018

PDF Pages: 326 Full Text (13278) Open Access

Review Article on Inborn Errors of Metabolism

Lysosomal storage disease overview

Angela Sun

Published online: 29 December 2018

PDF Pages: 476 Full Text (13280) Open Access

Original Article

One-year long-term clinical outcomes following diffractive trifocal toric intraocular lens implantation: retrospective observational case series study

Young-Sik Yoo, Dong Won Paik, Dong Hui Lim, Tae-Young Chung

Published online: 15 November 2022

PDF Pages: 1159 Full Text (13261) Reporting Checklist Data Sharing Statement COI Form Open Access

Case Report

A brother and sister with breast cancer, BRCA2 mutations and bilateral supernumerary nipples

Michael McKay, Ryan Coad

Published online: 15 March 2017

PDF Pages: 106 Full Text (13147) Open Access

Review Article

MDA5 autoantibody—another indicator of clinical diversity in dermatomyositis

Richard D. Sontheimer

Published online: 14 April 2017

PDF Pages: 160 Full Text (13116) Open Access

Review Article

Circulating tumor cells and epithelial, mesenchymal and stemness markers: characterization of cell subpopulations

Guislaine Barriere, Pietro Fici, Giulia Gallerani, Francesco Fabbri, Wainer Zoli, Michel Rigaud

Published online: 26 November 2014

PDF Pages: 109 Full Text (13127) Open Access

Original Article

Risk factors of postoperative nausea and vomiting after total hip arthroplasty or total knee arthroplasty: a retrospective study

Yingjie Wang, Qi Yang, Jin Lin, Wenwei Qian, Jin Jin, Peng Gao, Baozhong Zhang, Bin Feng, Xisheng Weng

Published online: 15 September 2020

PDF Pages: 1088 Full Text (13179) Reporting Checklist Data Sharing Statement COI Form Open Access

Review Article on Medical Artificial Intelligent Research

The combination of brain-computer interfaces and artificial intelligence: applications and challenges

Xiayin Zhang, Ziyue Ma, Huaijin Zheng, Tongkeng Li, Kexin Chen, Xun Wang, Chenting Liu, Linxi Xu, Xiaohang Wu, Duoru Lin, Haotian Lin

Published online: 15 June 2020

PDF Pages: 712 Full Text (13137) COI Form Open Access

Review Article

Genetics and epigenetic factors of Wilson disease

Valentina Medici, Janine M. LaSalle

Published online: 30 April 2019

PDF Pages: S58 Full Text (13074) Open Access

Review Article on MET as Actionable Target in Cancer Therapy

MET: roles in epithelial-mesenchymal transition and cancer stemness

Hye-Min Jeon, Jeongwu Lee

Published online: 13 January 2017

PDF Pages: 5 Full Text (13075) Open Access

Review Article

Multisystem late onset Pompe disease (LOPD): an update on clinical aspects

Antonio Toscano, Carmelo Rodolico, Olimpia Musumeci

Published online: 15 July 2019

PDF Pages: 284 Full Text (12987) Open Access

Review Article

Ventilator-induced lung injury and lung mechanics

Jason H. T. Bates, Bradford J. Smith

Published online: 15 October 2018

PDF Pages: 378 Full Text (12927) Open Access

Original Article

Preliminary study to identify severe from moderate cases of COVID-19 using combined hematology parameters

Changzheng Wang, Rongrong Deng, Liyao Gou, Zhongxiao Fu, Xiaomei Zhang, Feng Shao, Guanzhen Wang, Weiyang Fu, Jianping Xiao, Xiao Ding, Tao Li, Xiulin Xiao, Chengbin Li

Published online: 14 May 2020

PDF Pages: 593 Full Text (12872) Reporting Checklist Data Sharing Statement COI Form Open Access

Review Article

Patient-related medical risk factors for periprosthetic joint infection of the hip and knee

Aleeson Eka, Antonia F. Chen

Published online: 25 September 2015

PDF Pages: 233 Full Text (12844) Open Access

Review Article

Possible mechanisms of action of mushroom-derived glucans on inflammatory bowel disease and associated cancer

Betty Schwartz, Yitzhak Hadar

Published online: 27 February 2014

PDF Pages: 19 Full Text (12846) Open Access

Review Article

The female urinary microbiota, urinary health and common urinary disorders

Linda Brubaker, Alan J. Wolfe

Published online: 19 January 2017

PDF Pages: 34 Full Text (12877) Open Access

Editorial

Endoscopic management of esophagogastric varices in Japan

Hisamitsu Miyaaki, Tatsuki Ichikawa, Naota Taura, Satoshi Miuma, Hajime Isomoto, Kazuhiko Nakao

Published online: 29 May 2014

PDF Pages: 42 Full Text (12817) Open Access

Review Article on Innovations and Technology in Surgery

Laser applications in surgery

Beina Azadgoli, Regina Y. Baker

Published online: 19 December 2016

PDF Pages: 452 Full Text (12733) Open Access

Guideline

Guidelines for the diagnosis and treatment of osteoarthritis in China (2019 edition)

Zhiyi Zhang, Cibo Huang, Quan Jiang, Yi Zheng, Yi Liu, Shengyun Liu, Yingjuan Chen, Yifang Mei, Changhai Ding, Min Chen, Xin Gu, Dan Xing, Min Gao, Lan He, Zhizhong Ye, Lijun Wu, Jianhua Xu, Pinting Yang, Xuewu Zhang, Yue Zhang, Jinwei Chen, Jin Lin, Like Zhao, Mengtao Li, Wanling Yang, Yixin Zhou, Qing Jiang, Cong-Qiu Chu, Yaolong Chen, Weiya Zhang, Wei-Chung Tsai, Guanghua Lei, Dongyi He, Wei Liu, Yongfei Fang, Darong Wu, Jianhao Lin, Cheng-Chung Wei, Hsiao-Yi Lin, Xiaofeng Zeng

Published online: 15 October 2020

PDF Pages: 1213 Full Text (12728) Reporting Checklist COI Form Open Access