Most Read article list (ranking real-time pageviews since the publication of the article)

  
Review Articles on Treatment for Hepatitis B
Hepatitis B: progress in understanding chronicity, the innate immune response, and cccDNA protection
Kenichi Morikawa, Tomoe Shimazaki, Rei Takeda, Takaaki Izumi, Machiko Umumura, Naoya Sakamoto
Published online: 27 September 2016
Review Article
State of the art management of metastatic gastroesophageal cancer
Adrian G. Murphy, David Lynch, Ronan J. Kelly
Published online: 25 September 2015
Highlighted Reports in Galectins
Galectins in tumor angiogenesis
Arjan W. Griffioen, Victor L. Thijssen
Published online: 20 September 2014
Review Article
Objective and quantitative assessment of motor function in Parkinson’s disease—from the perspective of practical applications
Ke Yang, Wei-Xi Xiong, eng-Tao Liu, Yi-Min Sun, Susan Luo, Zheng-Tong Ding, Jian-Jun Wu, Jian Wang
Published online: 11 March 2016
Review Article on Advances in Laboratory Tests for Infectious Diseases
Diagnostic markers for community-acquired pneumonia
Akihiro Ito, Tadashi Ishida
Published online: 14 May 2020
Review Article
Solid organ transplantation in the 21st century
Cara K. Black, Kareem M. Termanini, Oswaldo Aguirre, Jason S. Hawksworth, Michael Sosin
Published online: 26 October 2018
Big-data Clinical Trial Column
Overview of model validation for survival regression model with competing risks using melanoma study data
Zhongheng Zhang, Giuliana Cortese, Christophe Combescure, Roger Marshall, Minjung Lee, Hyun Ja Lim, Bernhard Haller, written on behalf of AME Big-Data Clinical Trial Collaborative Group
Published online: 30 August 2018
Review Articles on Innovations & Technology in Surgery
Surgical research using national databases
Ram K. Alluri, Hyuma Leland, Nathanael Heckmann
Published online: 31 October 2016
Review Article
The dual role of complement in cancer and its implication in anti-tumor therapy
Ioannis Kourtzelis, Stavros Rafail
Published online: 28 July 2016
Original Article
The effects of midazolam or propofol plus fentanyl on ICU mortality: a retrospective study based on the MIMIC-IV database
Wen Sun, Yang Yan, Shidong Hu, Boyan Liu, Shuying Wang, Wenli Yu, Songyan Li
Published online: 28 February 2022
Original Article
Non-operative treatment options for knee osteoarthritis
Michael DeRogatis, Hiba K. Anis, Nipun Sodhi, Joseph O. Ehiorobo, Morad Chughtai, Anil Bhave, Michael A. Mont
Published online: 23 October 2019
Review Article on Toward Precision Medicine in Neurological Diseases
Toward precision medicine in amyotrophic lateral sclerosis
Zhang-Yu Zou, Chang-Yun Liu, Chun-Hui Che, Hua-Pin Huang
Published online: 27 January 2016
Original Article
Efficacy and safety of antibiotic agents in children with COVID-19: a rapid review
Jianjian Wang, Yuyi Tang, Yanfang Ma, Qi Zhou, Weiguo Li, Muna Baskota, Yinmei Yang, Xingmei Wang, Qingyuan Li, Xufei Luo, Toshio Fukuoka, Hyeong Sik Ahn, Myeong Soo Lee, Zhengxiu Luo, Enmei Liu, Yaolong Chen, on behalf of COVID-19 Evidence and Recommendations Working Group
Published online: 29 May 2020
Review Article
Paradigms lost—an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis
Astrid O. Leech, Rodrigo G.B. Cruz, Arnold D.K. Hill, Ann M. Hopkins
Published online: 15 August 2015
Surgical Technique
Laparoscopic hernioplasty of hiatal hernia
Xuefei Yang, Rong Hua, Kai He, Qiwei Shen, Qiyuan Yao
Published online: 27 September 2016
Review Article on Rheumatologic Skin Disease
Environmental triggers of dermatomyositis: a narrative review
Christina E. Bax, Spandana Maddukuri, Adarsh Ravishankar, Lisa Pappas-Taffer, Victoria P. Werth
Published online: 15 March 2021
Review Article
Questions and challenges associated with studying the microbiome of the urinary tract
Yige Bao, Kait F. Al, Ryan M. Chanyi, Samantha Whiteside, Malcom Dewar, Hassan Razvi, Gregor Reid, Jeremy P. Burton
Published online: 19 January 2017
Big-data Clinical Trial Column
Residuals and regression diagnostics: focusing on logistic regression
Zhongheng Zhang
Published online: 25 May 2016
Original Article
Rate of early onset Alzheimer’s disease: a systematic review and meta-analysis
Xi-Chen Zhu, Lan Tan, Hui-Fu Wang, Teng Jiang, Lei Cao, Chong Wang, Jun Wang, Chen-Chen Tan, Xiang-Fei Meng, Jin-Tai Yu
Published online: 10 March 2015
Original Article
The difference between fasting and non-fasting lipid measurements is not related to statin treatment
Ming-Ming Liu, Jia Peng, Ye-Xuan Cao, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Ying Gao, Jian-Jun Li
Published online: 15 March 2021
Review Article on Endoscopic Therapy
New photodynamic therapy with next-generation photosensitizers
Hiromi Kataoka, Hirotada Nishie, Noriyuki Hayashi, Mamoru Tanaka, Akihiro Nomoto, Shigenobu Yano, Takashi Joh
Published online: 28 April 2017
Review Article
Uncovering the pathophysiology of irritable bowel syndrome by exploring the gut-brain axis: a narrative review
He-Yong Tang, Ai-Juan Jiang, Xi-Yang Wang, Hao Wang, Yuan-Yuan Guan, Fei Li, Guo-Ming Shen
Published online: 29 July 2021
Review Article
Beyond PD-L1 testing-emerging biomarkers for immunotherapy in non-small cell lung cancer
Khinh Ranh Voong, Josephine Feliciano, Daniel Becker, Benjamin Levy
Published online: 19 September 2017
Review Article
Prognostic biomarkers in acute coronary syndrome
Gian Luca Salvagno, Chiara Pavan
Published online: 15 July 2016
Review Article
The role of genetics and antibodies in sepsis
Evangelos J. Giamarellos-Bourboulis, Steven M. Opal
Published online: 13 September 2016
Big-data Clinical Trial Column
Principal components analysis in clinical studies
Zhongheng Zhang, Adela Castelló
Published online: 15 August 2017
Visualized Surgery
Acute incarcerated external abdominal hernia
Xue-Fei Yang, Jia-Lin Liu
Published online: 26 November 2014
Review Article
Non-invasive biomarkers in pancreatic cancer diagnosis: what we need versus what we have
Marta Herreros-Villanueva, Luis Bujanda
Published online: 16 April 2016
Review Article
Predictive factors for immunotherapy in melanoma
Cristina Teixidó, Maria González-Cao, Niki Karachaliou, Rafael Rosell
Published online: 14 September 2015
Perspective
RNAs that make a heart beat
Mithun Mitra, Hilary A. Coller
Published online: 19 December 2016
Editorial
The promise of an augmented reality game—Pokémon GO
Ji-Young An, Claudio R. Nigg
Published online: 15 May 2017
Editorial
Hypertension and left ventricular hypertrophy
Wilbert S. Aronow
Published online: 06 August 2017
Original Article
The accuracy of MRI in the diagnosis of anterior cruciate ligament injury
Mengou Zhao, Ying Zhou, Junru Chang, Jie Hu, Huixia Liu, Shuhang Wang, Donglei Si, Yaqin Yuan, Haiyan Li
Published online: 31 December 2020
Review Article
New role of biomarkers: mid-regional pro-adrenomedullin, the biomarker of organ failure
Francisco Valenzuela-Sánchez, Blanca Valenzuela-Méndez, Juan Francisco Rodríguez-Gutiérrez, Ángel Estella-García, María Ángela González-García
Published online: 13 September 2016
Review Article
Human papilloma virus (HPV) profiles in breast cancer: future management
Md. Saimul Islam, Balarko Chakraborty, Chinmay Kumar Panda
Published online: 29 May 2020
Review Article
Current anti-copper therapies in management of Wilson disease
Isabelle Mohr, Karl Heinz Weiss
Published online: 30 April 2019
Review Article
The combination of checkpoint immunotherapy and targeted therapy in cancer
Niki Karachaliou, Maria Gonzalez Cao, Aaron Sosa, Jordi Berenguer, Jillian Wilhelmina Paulina Bracht, Masaoki Ito, Rafael Rosell
Published online: 28 September 2017
Review Article on Mesothelioma
Diagnosis and prognosis—review of biomarkers for mesothelioma
Huan H. Sun, Allen Vaynblat, Harvey I. Pass
Published online: 15 June 2017
Review Article
New tools for Wilson’s disease diagnosis: exchangeable copper fraction
France Woimant, Nouzha Djebrani-Oussedik, Aurélia Poujois
Published online: 30 April 2019
Review Article
Subglottic secretion drainage for ventilator-associated pneumonia prevention: an underused efficient measure
Jean-Claude Lacherade, Marie-Ange Azais, Caroline Pouplet, Gwenhael Colin
Published online: 13 November 2018
Review Article
Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance
Anna Martinez-Cardús, Miguel Vizoso, Sebastian Moran, Jose Luis Manzano
Published online: 14 September 2015
Review Article on Pain Therapy
Advances in the interventional management of neuropathic pain
Vishal Varshney, Jill Osborn, Rahul Chaturvedi, Vrajesh Shah, Krishnan Chakravarthy
Published online: 30 January 2021
Original Article
Effectiveness of Chinese herbal medicine combined with Western medicine on deferring dialysis initiation for nondialysis chronic kidney disease stage 5 patients: a multicenter prospective nonrandomized controlled study
Yifan Wu, Chuang Li, Lei Zhang, Chuan Zou, Peng Xu, Zehuai Wen, Wenwei Ouyang, Nizhi Yang, Min Zhang, Qizhan Lin, Fuhua Lu, Lixin Wang, Kun Bao, Daixin Zhao, Lizhe Fu, Xinfeng Guo, Lihong Yang, Aihua Ou, Zehui He, Heng Weng, Jianmin Li, Wei Shi, Xiaoqin Wang, Liqun Song, Yongli Zhan, Wei Sun, Lianbo Wei, Niansong Wang, Dingkun Gui, Jihong Zhan, Ying Lu, Hongyu Chen, Yuning Liu, Hongtao Yang, Ming Chen, Yiping Wang, Peiqing Zhang, Yueyi Deng, Lanfen Meng, Xiaohong Cheng, Feng Li, Dajun Yu, Damin Xu, Jing’ai Fang, Hongyan Li, Junzhou Fu, Yuansheng Xie, Wenge Li, Jinghong Zhao, Yuanhang Huang, Zhaoyu Lu, Guobin Su, La Zhang, Xindong Qin, Yuan Xu, Yu Peng, Haijing Hou, Lili Deng, Hui Liu, Xina Jie, Lichang Liu, Fang Tang, Hongfei Pei, Ping Li, Wei Mao, Xusheng Liu
Published online: 30 March 2021
Review Article on Cardiopulmonary Interactions
Heart-Lung interaction in spontaneous breathing subjects: the basics
Sheldon Magder
Published online: 27 September 2018
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