Vol 10, No 22 (November 29, 2022): Annals of Translational Medicine

Editorial

Mechanisms of airway remodeling converge at the critical point of bronchoconstriction in asthma
Tilo Winkler
Annals of Translational Medicine
 2022;
10
(22)
:1188
(November 2022)
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Airway remodeling in asthma
Carolyn Damilola Ekpruke, Patricia Silveyra
Annals of Translational Medicine
 2022;
10
(22)
:1189
(November 2022)
PDF Pages: 1189 Full Text (1097) COI Form Open Access Get Permission
Epigenetics of asthma—the field continues to evolve
Deepa Rastogi
Annals of Translational Medicine
 2022;
10
(22)
:1190
(November 2022)
PDF Pages: 1190 Full Text (588) COI Form Open Access Get Permission

Original Article

Particle beam radiation therapy for head and neck rhabdomyosarcoma in adults
Jing Yang, Jing Gao, Jiyi Hu, Weixu Hu, Xianxing Qiu, Qingting Huang, Lin Kong, Jiade J. Lu
Annals of Translational Medicine
 2022;
10
(22)
:1191
(November 2022)
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A cross-sectional analysis of registered clinical trials on the use of particle beam radiation therapy in head and neck cancers
Wenna Zhang, Lin Kong, Jiade J. Lu
Annals of Translational Medicine
 2022;
10
(22)
:1192
(November 2022)
PDF Pages: 1192 Full Text (788) COI Form Open Access Get Permission
Carbon-ion radiotherapy boost with standard dose proton radiation for incomplete-resected high-grade glioma: a phase 1 study
Xianxin Qiu, Jing Gao, Jing Yang, Jiyi Hu, Weixu Hu, Qingting Huang, Lin Kong, Jiade J. Lu
Annals of Translational Medicine
 2022;
10
(22)
:1193
(November 2022)
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Development of a normal tissue complication probability (NTCP) model using an artificial neural network for radiation-induced necrosis after carbon ion re-irradiation in locally recurrent nasopharyngeal carcinoma
Tian Wang, Jiyi Hu, Qingting Huang, Weiwei Wang, Xiyu Zhang, Liwen Zhang, Xiaodong Wu, Lin Kong, Jiade Jay Lu
Annals of Translational Medicine
 2022;
10
(22)
:1194
(November 2022)
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Intensity-modulated proton and carbon-ion radiation therapy in the management of major salivary gland carcinomas
Qingting Huang, Weixu Hu, Jiyi Hu, Jing Gao, Jing Yang, Xianxin Qiu, Lin Kong, Jiade Jay Lu
Annals of Translational Medicine
 2022;
10
(22)
:1195
(November 2022)
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Pre-treatment FLT-PET parameters as a prognostic tool for patients with locally advanced recurrent nasopharyngeal carcinoma salvaged by carbon-ion radiotherapy: a pilot study
Jiyi Hu, Zhongyi Yang, Jing Gao, Weixu Hu, Jing Yang, Xianxin Qiu, Guang Ma, Lin Kong, Jiade J. Lu
Annals of Translational Medicine
 2022;
10
(22)
:1196
(November 2022)
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Comparison of the efficacy and toxicity of postoperative proton versus carbon ion radiotherapy for head and neck cancers
Qingting Huang, Jiyi Hu, Weixu Hu, Jing Gao, Jing Yang, Xianxin Qiu, Jiade Jay Lu, Lin Kong
Annals of Translational Medicine
 2022;
10
(22)
:1197
(November 2022)
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The role of carbon-ion radiotherapy in the treatment of adenoid cystic carcinoma of the nasopharynx
Jiyi Hu, Weixu Hu, Jing Gao, Jing Yang, Xianxin Qiu, Qingting Huang, Lin Kong, Jiade J. Lu
Annals of Translational Medicine
 2022;
10
(22)
:1198
(November 2022)
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Perfusion MR prior to radiotherapy is a strong predictor of survival in high-grade gliomas after proton and carbon ion radiotherapy
Xianxin Qiu, Jing Gao, Jing Yang, Jiyi Hu, Weixu Hu, Xiaoyong Zhang, Jiade J. Lu, Lin Kong
Annals of Translational Medicine
 2022;
10
(22)
:1199
(November 2022)
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Carbon-ion radiotherapy in the treatment of radiation-induced second primary malignancies
Jing Yang, Jing Gao, Jiyi Hu, Weixu Hu, Xianxin Qiu, Qingting Huang, Lin Kong, Jiade J. Lu
Annals of Translational Medicine
 2022;
10
(22)
:1200
(November 2022)
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MiR-148a-3p attenuates apoptosis and inflammation by targeting CNTN4 in atherosclerosis
Kai Wang, Xi-Tong Huang, Yan-Ping Miao, Xiao-Long Bai, Feng Jin
Annals of Translational Medicine
 2022;
10
(22)
:1201
(November 2022)
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NLRP3 mediates trophoblastic inflammasome activation and protects against Listeria monocytogenes infection during pregnancy
Yu Gao, Min Zhou, Wen Zhang, Jinxing Jiang, Zhibin Ouyang, Yuanfang Zhu, Ning Li
Annals of Translational Medicine
 2022;
10
(22)
:1202
(November 2022)
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FGF10 mediates protective anti-oxidative effects in particulate matter-induced lung injury through Nrf2 and NF-κB signaling
Qiang Wang, Qiangqiang Shi, Li Liu, Yao Qian, Nian Dong
Annals of Translational Medicine
 2022;
10
(22)
:1203
(November 2022)
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Identification of key genes associated with cancer stem cell characteristics in Wilms’ tumor based on bioinformatics analysis
Cheng Su, Jie Zheng, Siyu Chen, Jinwei Tuo, Jinxia Su, Xiuyi Ou, Shaohua Chen, Congjun Wang
Annals of Translational Medicine
 2022;
10
(22)
:1204
(November 2022)
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PCSK9 inhibitor inclisiran for treating atherosclerosis via regulation of endothelial cell pyroptosis
Ni Kong, Qin Xu, Wei Cui, Xiaoying Feng, Huijie Gao
Annals of Translational Medicine
 2022;
10
(22)
:1205
(November 2022)
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Long-term clinical outcomes of Chinese diabetic patients after coronary revascularization with drug-eluting stents: a retrospective comparative cohort study
Yanping Li, Jixuan Liu, Yupeng Du, Duan Lei, Hongbin Liu
Annals of Translational Medicine
 2022;
10
(22)
:1206
(November 2022)
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Water search and rescue (SAR) for ship accidents in China: analysis of 12 years’ data
Jie Huang, Ning Han, Bi-Qing Jiang, Yan Cao, Xiao-Tong Han
Annals of Translational Medicine
 2022;
10
(22)
:1207
(November 2022)
PDF Pages: 1207 Full Text (1317) Reporting Checklist COI Form Open Access Get Permission
Does a longer second stage of labor worsen umbilical artery blood gas parameters in newborns?—a retrospective cohort study of 2,140 cases
Chuo Li, Tiantian He, Jin Zhou, Zhangmin Tan, Peizhen Zhang, Yuzhu Yin
Annals of Translational Medicine
 2022;
10
(22)
:1208
(November 2022)
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Relationship between hysterectomy and stroke in National Health and Nutrition Examination Survey (NHANES) 2007–2018: a cross-sectional study
Kun Cheng, Xiaojun Liu
Annals of Translational Medicine
 2022;
10
(22)
:1209
(November 2022)
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Flurbiprofen axetil alleviates the effect of formalin-induced inflammatory pain on the cognitive function of rats with mild cognitive impairment through the AMPKα/NF-κB signaling pathway
Linshen Huang, Xiaohong Zheng, Yanping Zhang, Yuerong Lin, Lanying Lin, Youguang Gao, Xianzhong Lin
Annals of Translational Medicine
 2022;
10
(22)
:1210
(November 2022)
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Clinical retrospective study on the efficacy and safety of endoscopic ear surgery for adhesive otitis media
Ya-Nan Guo, Minfei Qian, Jiping Li, Ji Xu, Hao Chen, Hua Zhang
Annals of Translational Medicine
 2022;
10
(22)
:1211
(November 2022)
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Comparison of risk of peritoneal dialysis-associated peritonitis between roxadustat and recombinant human erythropoietin in peritoneal dialysis patients: a retrospective comparative cohort study
Wei Zhang, Yanhong Tan, Jun Ai, Fuzhang Luo, Xiaoyan Su, Qimeng Wu, Lijuan Su, Jianyi Pan, Qingkun Zheng, Bin Li, Jiayi Chen, Qimei Luo, Jinzhong Chen, Xianrui Dou
Annals of Translational Medicine
 2022;
10
(22)
:1212
(November 2022)
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Spermine synthase (SMS) serves as a prognostic biomarker in head and neck squamous cell carcinoma: a bioinformatics analysis
Xiaoyu Pan, Lijun Xue, Yihan Sun
Annals of Translational Medicine
 2022;
10
(22)
:1213
(November 2022)
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MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis
Du-Jiang Yang, Xiao-Dong Wang, Xiao-Ying Fu, Hui-Min Lu, Zong-Guang Zhou, Yong Liu
Annals of Translational Medicine
 2022;
10
(22)
:1214
(November 2022)
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Single-cell transcriptomic, transcriptomic, and metabolomic characterization of human atherosclerosis
Xiaoyang Liu, Li Li, Yiru Yin, Likui Zhang, Wenhao Wang
Annals of Translational Medicine
 2022;
10
(22)
:1215
(November 2022)
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Isorhamnetin inhibits progression of ovarian cancer by targeting ESR1
Manman Wang, Zhengtan Xu, Qi Cai, Yanmei Deng, Weiqiao Shi, Hongyu Zhou, Dajiang Wang, Jian Li
Annals of Translational Medicine
 2022;
10
(22)
:1216
(November 2022)
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Efficacy and safety of auto-cross-linked hyaluronic gel to prevent intrauterine adhesion after hysteroscopic electrosurgical resection: a multi-center randomized controlled trial
Hengxi Chen, Wei Xiong, Yuhua Zeng, Haihong Du, Lin Ye, Liang Chen, Jia Chen, Yana Liu, Meiqin Gong, Xue Dong, Jie Liu, Xin Tan
Annals of Translational Medicine
 2022;
10
(22)
:1217
(November 2022)
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BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson’s disease
Zhong-Ming Ying, Qian-Kun Lv, Xiao-Yu Yao, An-Qi Dong, Ya-Ping Yang, Yu-Lan Cao, Fen Wang, Ai-Ping Gong, Chun-Feng Liu
Annals of Translational Medicine
 2022;
10
(22)
:1218
(November 2022)
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Sinuvertebral nerve block treats discogenic low back pain: a retrospective cohort study
Zezheng Liu, Runxun Ma, Chaohui Fan, Junjie Chen, Rusen Zhang, Zhiyang Zheng, Yejie Xu, Zexian Liu, Qinghao Zhao, Qingchu Li
Annals of Translational Medicine
 2022;
10
(22)
:1219
(November 2022)
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18F-FDG PET/CT and MR imaging features of liver metastases in gastrointestinal stromal tumors: a cross-sectional analysis
Qinghu Lyu, Duanyu Lin, Mingdeng Tang, Daojia Liu, Jieping Zhang, Yuntao Wang, Vishal G. Shelat, Driss Raissi, Vikas Ostwal, Xingfa Chen, Shengxu Li
Annals of Translational Medicine
 2022;
10
(22)
:1220
(November 2022)
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Development and validation of the prediction models for preeclampsia: a retrospective, single-center, case-control study
Xuhong Chen, Li Yuan, Zhen Ji, Xiyun Bian, Shaofang Hua
Annals of Translational Medicine
 2022;
10
(22)
:1221
(November 2022)
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Patterns of care and prognostic evaluation for stage I–III upper esophageal squamous cell carcinoma: a population-based study
Dongbo Chen, Xiaozhu Zha, Dongmei Ye, Mei Kang, Liyang Zhu, Mingwei Yang, Yu Chen, Kechao Zhu, Wanli Xia, Zhi Wang, Yichun Wang
Annals of Translational Medicine
 2022;
10
(22)
:1222
(November 2022)
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Effects of short-term waterfall forest aerosol air exposure on rat lung proteomics
Zixin Zhu, Xueke Zhao, Lili Zhu, Yan Xiong, Shuo Cong, Mingyu Zhou, Manman Zhang, Mingliang Cheng, Xinhua Luo
Annals of Translational Medicine
 2022;
10
(22)
:1223
(November 2022)
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Effect of Roxadustat versus erythropoietin (EPO) for treating anemia in patients with diabetic kidney disease: a retrospective cohort study
Lei Zhang, Yulu Liu, Ying Huang, Yuee Zhao, Cong Wei, Kexin Yang, Xiaohui Li, Shumin Zhang, Wenpeng Wang, Yu Liu, Fuyou Liu, Lin Sun, Li Xiao
Annals of Translational Medicine
 2022;
10
(22)
:1224
(November 2022)
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Oxygen pulse variation in symptomatic patients with suspected coronary artery disease: a diagnostic analysis
Shangwei Huang, Lijie Wang, Jimin Li, Lan Ma, Xiaoyan He, Qi Zhang, Ying Li
Annals of Translational Medicine
 2022;
10
(22)
:1225
(November 2022)
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Investigation of hub genes and immune infiltration in androgenetic alopecia using bioinformatics analysis
Yuan Zhou, Zhongbo Huang, Chen Wang, Jinping Su, Ping Jiang, Lili Li, Jinglin Qin, Zhi Xie
Annals of Translational Medicine
 2022;
10
(22)
:1226
(November 2022)
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Hypoxia-inducible factor 1α enhances RANKL-induced osteoclast differentiation by upregulating the MAPK pathway
Dong Wang, Lin Liu, Zechao Qu, Bo Zhang, Xiangcheng Gao, Wangli Huang, Mingzhe Feng, Yining Gong, Lingbo Kong, Yanjun Wang, Liang Yan
Annals of Translational Medicine
 2022;
10
(22)
:1227
(November 2022)
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Efficacy and safety of pyrotinib and radiotherapy vs. pyrotinib-based therapy in patients with HER2+ breast cancer with brain metastasis: a retrospective cohort study
Jiaxin Chen, Huiqiang Zhang, Jinmei Zhou, Zisheng Wu, Xuexue Wu, Shaohua Zhang, Zefei Jiang, Tao Wang
Annals of Translational Medicine
 2022;
10
(22)
:1228
(November 2022)
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Using arterial phase hyperenhancement on CT instead of gadoxetic acid arterial phase enhancement may improve the diagnostic performance for hepatocellular carcinoma
Hehan Tang, Feifei Gao, Yi Wei, Liping Deng, Qian Li, Yuan Yuan, Tong Zhang, Guoyong Chen, Shan Yao, Xiaocheng Wei, Lisha Nie, Bin Song, Zhenlin Li
Annals of Translational Medicine
 2022;
10
(22)
:1229
(November 2022)
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Microbiome and metabolome analysis to clarify the interaction between the urine microbiota and serum metabolites in Chinese patients with immunoglobulin A nephropathy
Shishi Li, Chiyu Ma, Yan Yang, Wanxia Cai, Weier Dai, Xinzhou Zhang, Lianghong Yin, Donge Tang, Fanna Liu, Yong Dai
Annals of Translational Medicine
 2022;
10
(22)
:1230
(November 2022)
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Comparison between free posterior tibial flap and free radial forearm flap for head and neck reconstruction: an anatomical study and a retrospective comparative cohort study
Qi Zhong, Jugao Fang, Zhigang Huang, Yang Zhang, Shizhi He, Yonggang Jin, Hongzhi Ma, Lizhen Hou, Wei Guo, Yuan Wang, Yurong He, Xiaoyan Wang
Annals of Translational Medicine
 2022;
10
(22)
:1231
(November 2022)
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Comprehensive analysis of cuproptosis-related lncRNAs in the prognosis and therapy response of patients with bladder cancer
Ding Li, Xuan Wu, Xinxin Fan, Cheng Cheng, Dongbei Li, Wenzhou Zhang
Annals of Translational Medicine
 2022;
10
(22)
:1232
(November 2022)
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The value of the Advanced Lung Cancer Inflammation Index (ALI) in assessing the prognosis of patients with hepatocellular carcinoma treated with camrelizumab: a retrospective cohort study
Qian Li, Fei Ma, Diamantis I. Tsilimigras, Fredrik Åberg, Ju Feng Wang
Annals of Translational Medicine
 2022;
10
(22)
:1233
(November 2022)
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Effects of β-blockers therapy on the 28-day and 3-year survival rates of end-stage renal disease patients with cardiovascular disease: a retrospective cohort study
Yong Wang, Zheqian Wu, Shijie Lu, Lili Yin, Yuandong Chen, Canyi Qiu, Pauline Yeung Ng, Koray Durak, Cristian Deana, Fei Ding, Zhiyan Zhang, Lihua Dai
Annals of Translational Medicine
 2022;
10
(22)
:1234
(November 2022)
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Clinical significance and immune landscape of cuproptosis-related lncRNAs in kidney renal clear cell carcinoma: a bioinformatical analysis
Ding Li, Xuan Wu, Wenping Song, Cheng Cheng, Lidan Hao, Wenzhou Zhang
Annals of Translational Medicine
 2022;
10
(22)
:1235
(November 2022)
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Chaetoglobosin E inhibits tumor growth and promotes the anti-tumor efficacy of cytotoxic drugs in esophageal squamous cell carcinoma by targeting PLK1
Jin-Hua Chen, Qing-Feng Guo, Qiu-Ge Liu, Bao-Xia He, Wen-Ping Song, Zhen-Hua Yin, Dong-Bei Li, Lin Chen, Wen-Zhou Zhang
Annals of Translational Medicine
 2022;
10
(22)
:1236
(November 2022)
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Newly found variations of the right posterior portal vein identified radiologically in 1,003 Chinese patients: a cross-sectional study
Jin-Yu Li, Wei-Dong Dai, Ji-Xiong Hu, Jiang-Sheng Huang, Xian-Ling Liu, Man-Jun Xiao, En-Hua Xiao, Ya-Jun Li, Xi-Long Mei, Kai Deng, Jing-Cheng Shi
Annals of Translational Medicine
 2022;
10
(22)
:1237
(November 2022)
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Targeted activation of ERK1/2 reduces ischemia and reperfusion injury in hyperglycemic myocardium by improving mitochondrial function
Fei Yu, Fen Liu, Jun-Yi Luo, Qian Zhao, Hong-Li Wang, Bin-Bin Fang, Xiao-Mei Li, Yi-Ning Yang
Annals of Translational Medicine
 2022;
10
(22)
:1238
(November 2022)
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The silencing of lnc-NONHSAT071210 suppresses the proliferation, fibrosis, migration, and invasion of TGFβ1-treated lung epithelial cells
Yuan Liu, Fuai Lu, Xiaofen Li, Youguo Yang, Jianqing Yang
Annals of Translational Medicine
 2022;
10
(22)
:1239
(November 2022)
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Glycolysis-related gene dihydrolipoamide acetyltransferase promotes poor prognosis in hepatocellular carcinoma through the Wnt/β-catenin and PI3K/Akt signaling pathways
Yuan Zhou, Haijuan Gu, Bingfeng Shao, Suqing Zhang, Harpreet Pall, Renata D’Alpino Peixoto, Shaffer R. S. Mok, Guodong Zhu
Annals of Translational Medicine
 2022;
10
(22)
:1240
(November 2022)
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Insufficient sleep disrupts glucose metabolism during pregnancy by inhibiting PGC-1α
Hao Wu, Cong Lu, Xing Li, Xianming Xu, Sufang Wu
Annals of Translational Medicine
 2022;
10
(22)
:1241
(November 2022)
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Corin is regulated by circ-0012397/miR-200a-3p and inhibits the oxygen-glucose deprivation-induced apoptosis of SHSY5Y neuroblastoma cells
Rui Yin, Caixia Qiu, Qikai Shen, Zhong Wang
Annals of Translational Medicine
 2022;
10
(22)
:1242
(November 2022)
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MiR-4291 stabilized the vulnerable atherosclerotic plaques by degrading the MAPK1/ERK2 in ApoE-/- mice
Yaqiong Jin, Jingchao Lu, Fan Liu, Xiuchun Yang, Fei Chen, Jie Zhang
Annals of Translational Medicine
 2022;
10
(22)
:1243
(November 2022)
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Efficacy and safety of different doses of remimazolam tosylate for colonoscopy: single-center, prospective, randomized, double-blind, parallel trial
Xiaoyan Zheng, Junhui Ji, Hao Cheng, Ke Peng, Linlin Liu, Fuhai Ji
Annals of Translational Medicine
 2022;
10
(22)
:1244
(November 2022)
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TGR5 overexpression mediated by the inhibition of transcription factor SOX9 protects against hypoxia-/reoxygenation-induced injury in hippocampal neurons by activating Nrf2/HO-1 signaling
Hong Jia, Yaoqi Chen, Yalin Liu
Annals of Translational Medicine
 2022;
10
(22)
:1245
(November 2022)
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Oncogenic alterations reveal key strategies for precision oncology in melanoma treatment
Wei Sun, Fang Zhao, Tu Hu, Zhiqiang Wu, Yu Xu, Yan Dong, Biqiang Zheng, Chunmeng Wang, Wangjun Yan, Xiaoli Zhu, Jian Wu, Michael J. McKay, Imanol Arozarena, Llucia Alos, Cristina Teixido, Yong Chen
Annals of Translational Medicine
 2022;
10
(22)
:1246
(November 2022)
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Modified pedicled temporoparietal fascial flap combined revascularization in adult moyamoya angiopathy
Wenchao Zhang, Xiaoguang Tong, Xuan Wang, Yang Sun, Tang Li
Annals of Translational Medicine
 2022;
10
(22)
:1247
(November 2022)
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Identification of the molecular mechanism and candidate markers for diabetic nephropathy
Chun Chen, Liping Liu, Jia Luo
Annals of Translational Medicine
 2022;
10
(22)
:1248
(November 2022)
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Multi-omics profiling identifies C1QA/B+ macrophages with multiple immune checkpoints associated with esophageal squamous cell carcinoma (ESCC) liver metastasis
Fei Zheng, Wei Zhang, Baihua Yang, Mingqiu Chen
Annals of Translational Medicine
 2022;
10
(22)
:1249
(November 2022)
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Review Article

Tissue factor as a new target for tumor therapy—killing two birds with one stone: a narrative review
Xiaoying Li, Dan Cao, Xiufeng Zheng, Gang Wang, Ming Liu
Annals of Translational Medicine
 2022;
10
(22)
:1250
(November 2022)
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A narrative review on the development of the ethical review mode of multicenter clinical trials in China
Jing Ding, Yashu Yin, Keke Fang, Wenzhou Zhang, Suxia Luo
Annals of Translational Medicine
 2022;
10
(22)
:1251
(November 2022)
PDF Pages: 1251 Full Text (1285) Reporting Checklist COI Form Open Access Get Permission

Special Report

Infection control management strategy for operating room during COVID-19 pandemic
Yihua Dai, Ru Zhang, Yanhua Jiang, Huidan Jin, Jingya Zhao, Anshun Guo, Xian Chen, Dongyi Fan, Lukun Yang
Annals of Translational Medicine
 2022;
10
(22)
:1252
(November 2022)
PDF Pages: 1252 Full Text (2040) COI Form Open Access Get Permission

Case Report

Creating a re-expanded prefabricated island flap constructed with an anastomosed vascular pedicle for burned ear reconstruction: a case report
Yang Chen, Wanfu Zhang, Fei Han, Xiaolong Hu, Lin Tong, Yunwei Wang, Shaohui Li, Peng Cao, Liwei Dong, Hao Guan
Annals of Translational Medicine
 2022;
10
(22)
:1253
(November 2022)
PDF Pages: 1253 Full Text (733) Reporting Checklist Peer Review File COI Form Open Access Get Permission
The efficacy of oxaliplatin, surufatinib, and camrelizumab on neuroendocrine carcinoma: a case report and literature review
Xianhua Wang, Shaobo Hu, Fei Su, Jie Lin, Jianghui Duan, Haidong Tan, Huangying Tan
Annals of Translational Medicine
 2022;
10
(22)
:1254
(November 2022)
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Annals of Translational Medicine
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iMDT Corner

Diabetic ketoacidosis induced by nivolumab in invasive mucinous adenocarcinoma of the lung: a case report and review of the literature
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Annals of Translational Medicine
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